Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3430310..3430455 Replicon chromosome
Accession NZ_CP100511
Organism Klebsiella pneumoniae strain LH50-a

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3430317..3430419 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3430310..3430455 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NLZ12_RS16830 (NLZ12_16830) 3425843..3427276 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
NLZ12_RS16835 (NLZ12_16835) 3427392..3427631 + 240 WP_002911393.1 YebV family protein -
NLZ12_RS16840 (NLZ12_16840) 3427729..3427920 + 192 WP_002911395.1 YebW family protein -
NLZ12_RS16845 (NLZ12_16845) 3427917..3428570 - 654 WP_020802220.1 protein-serine/threonine phosphatase -
NLZ12_RS16850 (NLZ12_16850) 3428727..3429695 + 969 WP_195770191.1 VirK/YbjX family protein -
NLZ12_RS16855 (NLZ12_16855) 3429800..3429943 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3430310..3430455 + 146 - - Antitoxin
- 3430317..3430419 - 103 - - Toxin
NLZ12_RS16860 (NLZ12_16860) 3430578..3430916 - 339 WP_016529031.1 YebY family protein -
NLZ12_RS16865 (NLZ12_16865) 3430933..3431802 - 870 WP_004189267.1 copper homeostasis membrane protein CopD -
NLZ12_RS16870 (NLZ12_16870) 3431806..3432180 - 375 WP_004151448.1 CopC domain-containing protein YobA -
NLZ12_RS16875 (NLZ12_16875) 3432293..3432523 + 231 WP_002911406.1 DNA polymerase III subunit theta -
NLZ12_RS16880 (NLZ12_16880) 3432602..3433261 + 660 WP_002911407.1 exodeoxyribonuclease X -
NLZ12_RS16885 (NLZ12_16885) 3433265..3435325 - 2061 WP_159307789.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T250713 NZ_CP100511:c3430419-3430317 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT250713 NZ_CP100511:3430310-3430455 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References