Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2991878..2992149 Replicon chromosome
Accession NZ_CP100500
Organism Escherichia coli strain LH50-c

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2991916..2992019 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2991878..2992149 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NLZ13_RS14745 2989035..2990474 + 1440 WP_001695829.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
NLZ13_RS14750 2990592..2990828 + 237 WP_001295499.1 YebV family protein -
NLZ13_RS14755 2990933..2991124 + 192 WP_001313035.1 YebW family protein -
NLZ13_RS14760 2991125..2991781 - 657 WP_000812739.1 protein-serine/threonine phosphatase -
- 2991878..2992149 + 272 - - Antitoxin
- 2991916..2992019 - 104 - - Toxin
NLZ13_RS14765 2992177..2992518 - 342 WP_000976472.1 YebY family protein -
NLZ13_RS14770 2992531..2993403 - 873 WP_000879287.1 copper homeostasis membrane protein CopD -
NLZ13_RS14775 2993407..2993781 - 375 WP_000168747.1 CopC domain-containing protein YobA -
NLZ13_RS14780 2993920..2994150 + 231 WP_000916760.1 DNA polymerase III subunit theta -
NLZ13_RS14785 2994252..2994908 + 657 WP_000011656.1 carbon-nitrogen hydrolase family protein YobB -
NLZ13_RS14790 2994932..2995594 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T250679 NZ_CP100500:c2992019-2991916 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT250679 NZ_CP100500:2991878-2992149 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References