250668

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 414610..415364 Replicon chromosome
Accession NZ_CP100500
Organism Escherichia coli strain LH50-c

Toxin (Protein)


Gene name ataT Uniprot ID -
Locus tag NLZ13_RS01935 Protein ID WP_001301452.1
Coordinates 414610..415095 (-) Length 162 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag NLZ13_RS01940 Protein ID WP_000801914.1
Coordinates 415086..415364 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NLZ13_RS01915 (409777) 409777..410535 + 759 WP_000815099.1 DeoR/GlpR family transcriptional regulator -
NLZ13_RS01920 (410517) 410517..412115 - 1599 WP_071337529.1 DNA-binding transcriptional regulator RtcR -
NLZ13_RS01925 (412302) 412302..413528 + 1227 WP_112037864.1 RNA-splicing ligase RtcB -
NLZ13_RS01930 (413532) 413532..414560 + 1029 WP_024257792.1 RNA 3'-terminal phosphate cyclase -
NLZ13_RS01935 (414610) 414610..415095 - 486 WP_001301452.1 GNAT family N-acetyltransferase Toxin
NLZ13_RS01940 (415086) 415086..415364 - 279 WP_000801914.1 DUF1778 domain-containing protein Antitoxin
NLZ13_RS01945 (415431) 415431..418136 - 2706 WP_048949104.1 HTH-type transcriptional regulator MalT -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(45-143)

Antitoxin

Vibrio phage ICP1, Orf50

(2-92)


Sequences

Toxin        


Download         Length: 162 a.a.        Molecular weight: 17650.57 Da        Isoelectric Point: 9.4066

>T250668 WP_001301452.1 NZ_CP100500:c415095-414610 [Escherichia coli]
MGITAPTPLTSEHNLADFCCSDHGMNEWLKKKALKNHSSGLSRVYVICIANTRQVIGYYCLSTGSIQRNLAPGAMRRNAP
ESLPVVVLGRLAIDQAWAGKGLGVALLKDAVYRTMSIAQQVGVRALIVHALDDSVRNFYLKYAFVPSPFQSLTLLYPITL
E

Download         Length: 486 bp

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10406.91 Da        Isoelectric Point: 4.6336

>AT250668 WP_000801914.1 NZ_CP100500:c415364-415086 [Escherichia coli]
MKPESKEAPINIRAKASQRDLIDMAANLVAKSRTDFMLDAACREAQDILLDQRLFIVDDEQYDAFLAALDAPITAERQAK
INALMNRKSPWE

Download         Length: 279 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References