Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2181592..2181760 Replicon chromosome
Accession NZ_CP100497
Organism Klebsiella michiganensis strain LH71

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2181650..2181753 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2181592..2181760 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NLZ14_RS10345 (NLZ14_10345) 2176719..2178779 + 2061 WP_033836507.1 oligopeptidase B -
NLZ14_RS10350 (NLZ14_10350) 2178786..2179445 - 660 WP_014229839.1 exodeoxyribonuclease X -
NLZ14_RS10355 (NLZ14_10355) 2179524..2179754 - 231 WP_004103351.1 DNA polymerase III subunit theta -
NLZ14_RS10360 (NLZ14_10360) 2179890..2180264 + 375 WP_014229838.1 CopC domain-containing protein YobA -
NLZ14_RS10365 (NLZ14_10365) 2180269..2181138 + 870 WP_254539957.1 copper homeostasis membrane protein CopD -
NLZ14_RS10370 (NLZ14_10370) 2181155..2181493 + 339 WP_254539958.1 YebY family protein -
- 2181592..2181760 - 169 - - Antitoxin
- 2181650..2181753 + 104 - - Toxin
NLZ14_RS10375 (NLZ14_10375) 2181878..2182837 - 960 WP_088168007.1 spore coat protein U domain-containing protein -
NLZ14_RS10380 (NLZ14_10380) 2182852..2185182 - 2331 WP_200914192.1 fimbria/pilus outer membrane usher protein -
NLZ14_RS10385 (NLZ14_10385) 2185185..2185949 - 765 WP_049102470.1 fimbria/pilus periplasmic chaperone -
NLZ14_RS10390 (NLZ14_10390) 2185968..2186486 - 519 WP_004852079.1 spore coat U domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T250656 NZ_CP100497:2181650-2181753 [Klebsiella michiganensis]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 169 bp

>AT250656 NZ_CP100497:c2181760-2181592 [Klebsiella michiganensis]
AACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTATAAGAATAGTTTACCGTGTCAGGTTTTCCAGTCCGCGACAAAAGTG
GACGAATAA

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References