Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ykfI-yfjZ/CbtA-CbeA
Location 3660131..3660810 Replicon chromosome
Accession NZ_CP100494
Organism Atlantibacter subterranea strain LH84-a

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag NLZ15_RS17225 Protein ID WP_254486853.1
Coordinates 3660469..3660810 (+) Length 114 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag NLZ15_RS17220 Protein ID WP_254486851.1
Coordinates 3660131..3660448 (+) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NLZ15_RS17190 (NLZ15_17190) 3655294..3655887 - 594 WP_254486843.1 hypothetical protein -
NLZ15_RS17195 (NLZ15_17195) 3655891..3657405 - 1515 WP_254486845.1 RNA-directed DNA polymerase -
NLZ15_RS17200 (NLZ15_17200) 3657941..3658213 - 273 WP_254486847.1 ogr/Delta-like zinc finger family protein -
NLZ15_RS17205 (NLZ15_17205) 3658494..3658697 - 204 WP_254486849.1 helicase -
NLZ15_RS17210 (NLZ15_17210) 3658723..3659935 + 1213 Protein_3372 IS3 family transposase -
NLZ15_RS17215 (NLZ15_17215) 3659951..3660112 + 162 WP_254489052.1 DUF987 family protein -
NLZ15_RS17220 (NLZ15_17220) 3660131..3660448 + 318 WP_254486851.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
NLZ15_RS17225 (NLZ15_17225) 3660469..3660810 + 342 WP_254486853.1 TA system toxin CbtA family protein Toxin
NLZ15_RS17230 (NLZ15_17230) 3661372..3661694 - 323 Protein_3376 hypothetical protein -
NLZ15_RS17235 (NLZ15_17235) 3661776..3663188 - 1413 WP_254486855.1 phage tail protein -
NLZ15_RS17240 (NLZ15_17240) 3663245..3663877 - 633 WP_254486857.1 hypothetical protein -
NLZ15_RS17245 (NLZ15_17245) 3663874..3664143 - 270 WP_254486859.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 3646655..3710384 63729


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-112)

Antitoxin

Antitoxin CbeA

(5-104)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12878.93 Da        Isoelectric Point: 9.6836

>T250650 WP_254486853.1 NZ_CP100494:3660469-3660810 [Atlantibacter subterranea]
MKLQPAATSRAVKPCLSPVAVWQMLLTRLLEQHYGLTLNDTPFSDETVIQKHIDAGITLINAVNFLVEKYELVRIDRRGF
SWQEQSPYLRAVDILRARQATGLLRQSCNNAVR

Download         Length: 342 bp

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 12025.67 Da        Isoelectric Point: 6.2025

>AT250650 WP_254486851.1 NZ_CP100494:3660131-3660448 [Atlantibacter subterranea]
MSNITWGLQRDITPRLGARLVQEGNRLQYLADQAIITGKFSDAECRKLDETFQHFISQMELMLTTGELNPRYTHCITLYH
NGFTCEADTLGSCGYVYIAIYPTQR

Download         Length: 318 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References