Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/PRK09812-MazE
Location 1718587..1719177 Replicon chromosome
Accession NZ_CP100494
Organism Atlantibacter subterranea strain LH84-a

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag NLZ15_RS08085 Protein ID WP_125292343.1
Coordinates 1718845..1719177 (+) Length 111 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag NLZ15_RS08080 Protein ID WP_125292508.1
Coordinates 1718587..1718844 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NLZ15_RS08055 (NLZ15_08055) 1714022..1714882 - 861 WP_254488186.1 metal ABC transporter permease -
NLZ15_RS08060 (NLZ15_08060) 1714879..1715679 - 801 WP_254488188.1 manganese/iron ABC transporter ATP-binding protein -
NLZ15_RS08065 (NLZ15_08065) 1715676..1716560 - 885 WP_254488976.1 metal ABC transporter substrate-binding protein -
NLZ15_RS08070 (NLZ15_08070) 1716833..1717765 + 933 WP_254488190.1 L,D-transpeptidase -
NLZ15_RS08075 (NLZ15_08075) 1717897..1718373 + 477 WP_254488192.1 hypothetical protein -
NLZ15_RS08080 (NLZ15_08080) 1718587..1718844 + 258 WP_125292508.1 antitoxin Antitoxin
NLZ15_RS08085 (NLZ15_08085) 1718845..1719177 + 333 WP_125292343.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
NLZ15_RS08095 (NLZ15_08095) 1719473..1720927 - 1455 WP_125292307.1 AMP nucleosidase -
NLZ15_RS08100 (NLZ15_08100) 1721324..1722439 + 1116 WP_144129118.1 branched-chain amino acid ABC transporter substrate-binding protein -
NLZ15_RS08105 (NLZ15_08105) 1722535..1723449 + 915 WP_125292305.1 branched-chain amino acid ABC transporter permease LivH -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(1-109)

Antitoxin

Antitoxin PemI-like

(4-84)


Sequences

Toxin        


Download         Length: 111 a.a.        Molecular weight: 11839.66 Da        Isoelectric Point: 10.2966

>T250642 WP_125292343.1 NZ_CP100494:1718845-1719177 [Atlantibacter subterranea]
MDRGEIWLVSLDPTAGHEQSGKRPVLIVSKASFNTFTRLPVVVPVTSGGHFARAAGFTVSLDGAGTKTTGVIRCDQPRTI
DMVARSGKRLERIPEAIVNEVLARLEAILN

Download         Length: 333 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9372.94 Da        Isoelectric Point: 4.7862

>AT250642 WP_125292508.1 NZ_CP100494:1718587-1718844 [Atlantibacter subterranea]
MYTTRLKKVGGSVMLTVPPAVLKTLGLTTDSEVGMTIDKGCLIIEAQKRPRYSLEELLAQCDPNAELSKEDREWIDAPPV
GKEIL

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References