Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 784235..784901 Replicon chromosome
Accession NZ_CP100494
Organism Atlantibacter subterranea strain LH84-a

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag NLZ15_RS03755 Protein ID WP_151602299.1
Coordinates 784482..784901 (+) Length 140 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag NLZ15_RS03750 Protein ID WP_125295342.1
Coordinates 784235..784501 (+) Length 89 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NLZ15_RS03725 (NLZ15_03725) 779447..780880 - 1434 WP_125295346.1 6-phospho-beta-glucosidase -
NLZ15_RS03730 (NLZ15_03730) 781004..781741 - 738 WP_192798679.1 MurR/RpiR family transcriptional regulator -
NLZ15_RS03735 (NLZ15_03735) 781855..782166 + 312 WP_220266523.1 N(4)-acetylcytidine aminohydrolase -
NLZ15_RS03740 (NLZ15_03740) 782296..782955 + 660 WP_125295344.1 hemolysin III family protein -
NLZ15_RS03745 (NLZ15_03745) 782990..783976 - 987 WP_254487737.1 tRNA-modifying protein YgfZ -
NLZ15_RS03750 (NLZ15_03750) 784235..784501 + 267 WP_125295342.1 FAD assembly factor SdhE Antitoxin
NLZ15_RS03755 (NLZ15_03755) 784482..784901 + 420 WP_151602299.1 protein YgfX Toxin
NLZ15_RS03760 (NLZ15_03760) 784906..785427 - 522 WP_254487738.1 flavodoxin FldB -
NLZ15_RS03765 (NLZ15_03765) 785529..786428 + 900 WP_254488883.1 site-specific tyrosine recombinase XerD -
NLZ15_RS03770 (NLZ15_03770) 786454..787167 + 714 WP_125295339.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
NLZ15_RS03775 (NLZ15_03775) 787171..788904 + 1734 WP_254487739.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(3-132)

Antitoxin

(7-79)


Sequences


Toxin        


Download         Length: 140 a.a.        Molecular weight: 16352.25 Da        Isoelectric Point: 11.0916

>T250641 WP_151602299.1 NZ_CP100494:784482-784901 [Atlantibacter subterranea]
VVLWQSDLRVSWRAQWFSLMLHGIVAAVILLLPWPLSYMPVWLVLLSLVVFDCVRSQRRIHSLQGEVKLTMDYRLRWQGV
EWELIGAPWMLQSGMLLRLRHPGTQRSQHLWLAADSMDASEWRDLRRVLLQQPQSGRPS

Download         Length: 420 bp


Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10491.99 Da        Isoelectric Point: 5.5535

>AT250641 WP_125295342.1 NZ_CP100494:784235-784501 [Atlantibacter subterranea]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDALSDDDKHVFIRLLECDDPDLFNWLMNHGKPADPELQRMVQLIQTRN
RDRGPVAI

Download         Length: 267 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References