Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 75738..76288 Replicon chromosome
Accession NZ_CP100494
Organism Atlantibacter subterranea strain LH84-a

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag NLZ15_RS00380 Protein ID WP_125292944.1
Coordinates 75977..76288 (+) Length 104 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag NLZ15_RS00375 Protein ID WP_125292827.1
Coordinates 75738..75974 (+) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NLZ15_RS00355 (NLZ15_00355) 71289..72323 - 1035 WP_125292831.1 L-rhamnose/proton symporter RhaT -
NLZ15_RS00360 (NLZ15_00360) 72522..73943 - 1422 WP_254487481.1 L-fucose/L-arabinose isomerase family protein -
NLZ15_RS00365 (NLZ15_00365) 74230..74850 + 621 WP_144131890.1 superoxide dismutase [Mn] -
NLZ15_RS00370 (NLZ15_00370) 74920..75609 + 690 WP_254487482.1 6-hydroxyaminopurine reductase -
NLZ15_RS00375 (NLZ15_00375) 75738..75974 + 237 WP_125292827.1 type II toxin-antitoxin system CcdA family antitoxin Antitoxin
NLZ15_RS00380 (NLZ15_00380) 75977..76288 + 312 WP_125292944.1 CcdB family protein Toxin
NLZ15_RS00385 (NLZ15_00385) 76327..77535 - 1209 WP_254489090.1 FMN-dependent L-lactate dehydrogenase LldD -
NLZ15_RS00390 (NLZ15_00390) 77535..78317 - 783 WP_125292826.1 transcriptional regulator LldR -
NLZ15_RS00395 (NLZ15_00395) 78314..79969 - 1656 WP_125292825.1 L-lactate permease -
NLZ15_RS00400 (NLZ15_00400) 80308..80670 - 363 WP_125292824.1 YibL family ribosome-associated protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-101)

Antitoxin

Post-segregation antitoxin CcdA

(8-78)


Sequences

Toxin        


Download         Length: 104 a.a.        Molecular weight: 11526.58 Da        Isoelectric Point: 6.9759

>T250639 WP_125292944.1 NZ_CP100494:75977-76288 [Atlantibacter subterranea]
MQFTVYKNTGRMALYPYVLNVQSDIIGRRTTRIVIPLFPLEKYMGPLADRLTPIVTVGPEKFVLMTHELASIPEKALGEE
ICSITSQRDVIKSALDFLLDGIG

Download         Length: 312 bp

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8859.98 Da        Isoelectric Point: 7.2018

>AT250639 WP_125292827.1 NZ_CP100494:75738-75974 [Atlantibacter subterranea]
MPALKRNKKTVTVTAAPELIQEAKAHGVNLSQTFENAIRAELHSIQVARWQKDNAQAIDYLNKLSEENGLFSDEYRTF

Download         Length: 237 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References