Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2202087..2202358 Replicon chromosome
Accession NZ_CP100486
Organism Escherichia coli strain LH85-a

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2202217..2202320 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2202087..2202358 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NLZ16_RS10470 2198642..2199304 - 663 WP_000944256.1 exodeoxyribonuclease X -
NLZ16_RS10475 2199328..2199984 - 657 WP_000011653.1 carbon-nitrogen hydrolase family protein YobB -
NLZ16_RS10480 2200086..2200316 - 231 WP_000916763.1 DNA polymerase III subunit theta -
NLZ16_RS10485 2200455..2200829 + 375 WP_000168747.1 CopC domain-containing protein YobA -
NLZ16_RS10490 2200833..2201705 + 873 WP_001551232.1 copper homeostasis membrane protein CopD -
NLZ16_RS10495 2201718..2202059 + 342 WP_000976472.1 YebY family protein -
- 2202087..2202358 - 272 - - Antitoxin
- 2202217..2202320 + 104 - - Toxin
NLZ16_RS10500 2202455..2203111 + 657 WP_001551231.1 protein-serine/threonine phosphatase -
NLZ16_RS10505 2203112..2203303 - 192 WP_001296140.1 YebW family protein -
NLZ16_RS10510 2203408..2203644 - 237 WP_001295499.1 YebV family protein -
NLZ16_RS10515 2203762..2205201 - 1440 WP_024186439.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2194777..2218198 23421
- inside Prophage - - 2178302..2218198 39896


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T250617 NZ_CP100486:2202217-2202320 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT250617 NZ_CP100486:c2202358-2202087 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References