250606

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yjhX-yjhQ/YjhX(toxin)
Location 4749009..4749828 Replicon chromosome
Accession NZ_CP100482
Organism Klebsiella grimontii strain LH87-a

Toxin (Protein)


Gene name yjhX Uniprot ID A0A9E1D5M6
Locus tag NLZ17_RS22925 Protein ID WP_004132607.1
Coordinates 4749571..4749828 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yjhQ Uniprot ID A0A9E1DGJ5
Locus tag NLZ17_RS22920 Protein ID WP_004132606.1
Coordinates 4749009..4749560 (-) Length 184 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NLZ17_RS22900 (NLZ17_22900) 4744398..4745795 + 1398 WP_004132593.1 MFS transporter -
NLZ17_RS22905 (NLZ17_22905) 4745919..4747259 + 1341 WP_049085654.1 carbohydrate porin -
NLZ17_RS22910 (NLZ17_22910) 4747363..4748109 - 747 WP_223226925.1 class I SAM-dependent methyltransferase -
NLZ17_RS22915 (NLZ17_22915) 4748539..4748895 - 357 Protein_4511 class I SAM-dependent methyltransferase -
NLZ17_RS22920 (NLZ17_22920) 4749009..4749560 - 552 WP_004132606.1 N-acetyltransferase Antitoxin
NLZ17_RS22925 (NLZ17_22925) 4749571..4749828 - 258 WP_004132607.1 YjhX family toxin Toxin
NLZ17_RS22930 (NLZ17_22930) 4750412..4751596 + 1185 WP_049085652.1 mannonate dehydratase -
NLZ17_RS22935 (NLZ17_22935) 4751673..4753148 + 1476 WP_148865109.1 fructuronate reductase -
NLZ17_RS22940 (NLZ17_22940) 4753285..4754061 + 777 WP_116944170.1 Uxu operon transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Putative toxin of bacterial toxin-antitoxin pair

(1-85)

Antitoxin

GNAT domain

(34-121)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9538.04 Da        Isoelectric Point: 11.1381

>T250606 WP_004132607.1 NZ_CP100482:c4749828-4749571 [Klebsiella grimontii]
MNLSRQEQRTLHVLAKGGRIAHVRDASGRVTSVECYSREGLLLSDCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRA
QLDNR

Download         Length: 258 bp

Antitoxin


Download         Length: 184 a.a.        Molecular weight: 19990.89 Da        Isoelectric Point: 7.2343

>AT250606 WP_004132606.1 NZ_CP100482:c4749560-4749009 [Klebsiella grimontii]
MTNHSFTFHVASEGDTNDILHVETRAFGYSKEARLVADLLNDESACPTLSLLARHNGKAVGHILFTRATFKGEPDSPMMH
ILAPLAVVPEYQGAGVGGGLIRHGIEQLKAMGSQTVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEALKACWMLQPLSS
QPLGRTGQIQCARALMKPEHWRE

Download         Length: 552 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References