Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2172784..2172952 Replicon chromosome
Accession NZ_CP100482
Organism Klebsiella grimontii strain LH87-a

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2172842..2172945 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2172784..2172952 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NLZ17_RS10505 (NLZ17_10505) 2167911..2169971 + 2061 WP_098065722.1 oligopeptidase B -
NLZ17_RS10510 (NLZ17_10510) 2169978..2170637 - 660 WP_004134816.1 exodeoxyribonuclease X -
NLZ17_RS10515 (NLZ17_10515) 2170716..2170946 - 231 WP_004103351.1 DNA polymerase III subunit theta -
NLZ17_RS10520 (NLZ17_10520) 2171082..2171456 + 375 WP_004134817.1 CopC domain-containing protein YobA -
NLZ17_RS10525 (NLZ17_10525) 2171461..2172330 + 870 WP_004134819.1 copper homeostasis membrane protein CopD -
NLZ17_RS10530 (NLZ17_10530) 2172347..2172685 + 339 WP_004103344.1 YebY family protein -
- 2172784..2172952 - 169 - - Antitoxin
- 2172842..2172945 + 104 - - Toxin
NLZ17_RS10535 (NLZ17_10535) 2173070..2174029 - 960 WP_049085573.1 spore coat protein U domain-containing protein -
NLZ17_RS10540 (NLZ17_10540) 2174044..2176374 - 2331 WP_098140854.1 fimbria/pilus outer membrane usher protein -
NLZ17_RS10545 (NLZ17_10545) 2176377..2177141 - 765 WP_004134823.1 fimbria/pilus periplasmic chaperone -
NLZ17_RS10550 (NLZ17_10550) 2177160..2177678 - 519 WP_032711055.1 spore coat U domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2101335..2182964 81629


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T250601 NZ_CP100482:2172842-2172945 [Klebsiella grimontii]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 169 bp

>AT250601 NZ_CP100482:c2172952-2172784 [Klebsiella grimontii]
AATAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTATAAGAATAGTTTACCGTGTCAGGTTTTCCAGTCCGTGACAAAAGTG
GACGAATAA

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References