Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1890339..1890484 | Replicon | chromosome |
| Accession | NZ_CP100478 | ||
| Organism | Klebsiella pneumoniae strain LH99-d | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1890375..1890477 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1890339..1890484 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NLZ18_RS09185 | 1885469..1887529 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| NLZ18_RS09190 | 1887533..1888192 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| NLZ18_RS09195 | 1888271..1888501 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| NLZ18_RS09200 | 1888614..1888988 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| NLZ18_RS09205 | 1888992..1889861 | + | 870 | WP_020956678.1 | copper homeostasis membrane protein CopD | - |
| NLZ18_RS09210 | 1889878..1890216 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 1890339..1890484 | - | 146 | - | - | Antitoxin |
| - | 1890375..1890477 | + | 103 | - | - | Toxin |
| NLZ18_RS09215 | 1890852..1890995 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| NLZ18_RS09220 | 1891100..1892068 | - | 969 | WP_254527536.1 | VirK/YbjX family protein | - |
| NLZ18_RS09225 | 1892225..1892878 | + | 654 | WP_032415192.1 | protein-serine/threonine phosphatase | - |
| NLZ18_RS09230 | 1892875..1893066 | - | 192 | WP_002911395.1 | YebW family protein | - |
| NLZ18_RS09235 | 1893164..1893403 | - | 240 | WP_002911393.1 | YebV family protein | - |
| NLZ18_RS09240 | 1893519..1894952 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T250586 NZ_CP100478:1890375-1890477 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT250586 NZ_CP100478:c1890484-1890339 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
