Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-VagC
Location 2751284..2751954 Replicon chromosome
Accession NZ_CP100476
Organism Mesorhizobium sp. C120A

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NL532_RS13345 Protein ID WP_023829215.1
Coordinates 2751556..2751954 (+) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NL532_RS13340 Protein ID WP_081730991.1
Coordinates 2751284..2751556 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NL532_RS13320 (NL532_13300) 2746485..2747627 - 1143 WP_023826558.1 hypothetical protein -
NL532_RS13325 (NL532_13305) 2747714..2749282 + 1569 WP_081730990.1 acyl--CoA ligase -
NL532_RS13330 (NL532_13310) 2749348..2749797 - 450 WP_023673075.1 Rrf2 family transcriptional regulator -
NL532_RS13335 (NL532_13315) 2750057..2751043 - 987 WP_023829213.1 sulfate ABC transporter substrate-binding protein -
NL532_RS13340 (NL532_13320) 2751284..2751556 + 273 WP_081730991.1 antitoxin Antitoxin
NL532_RS13345 (NL532_13325) 2751556..2751954 + 399 WP_023829215.1 type II toxin-antitoxin system VapC family toxin Toxin
NL532_RS13350 (NL532_13330) 2751969..2753018 - 1050 WP_023829216.1 sulfate/molybdate ABC transporter ATP-binding protein -
NL532_RS13355 (NL532_13335) 2753092..2753976 - 885 WP_023690809.1 sulfate ABC transporter permease subunit CysW -
NL532_RS13360 (NL532_13340) 2753969..2754820 - 852 WP_023687973.1 sulfate ABC transporter permease subunit CysT -
NL532_RS13365 (NL532_13345) 2754839..2755867 - 1029 WP_023829217.1 sulfate ABC transporter substrate-binding protein -
NL532_RS13370 (NL532_13350) 2756098..2756781 - 684 WP_023829218.1 M15 family metallopeptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-123)

Antitoxin

SpoVT-AbrB domain

(17-55)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 14123.38 Da        Isoelectric Point: 6.4544

>T250579 WP_023829215.1 NZ_CP100476:2751556-2751954 [Mesorhizobium sp. C120A]
MRFMLDTNILSDMIRNPAGKAASTAVRAGDGALCTSIVVASELRYGCARKGSAKLLAKVEQLLAELPVLPLDVPMDNEYG
ALRAELEARGQPIGHNDLFIAAHVCALGTTLVTANTGEFSRIKGLKVENWLE

Download         Length: 399 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10205.68 Da        Isoelectric Point: 5.6343

>AT250579 WP_081730991.1 NZ_CP100476:2751284-2751556 [Mesorhizobium sp. C120A]
MPQHRHSIPPPREAKLFRNNRSQAVRIPVEFELPGEKVLISRDGDRLVIEPVRKPGLTALLTQWAKEPPLGPEDDFPEIH
DAPVGPEDIF

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References