Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RelB(antitoxin)
Location 1864127..1864742 Replicon chromosome
Accession NZ_CP100430
Organism Streptococcus suis strain LSS42

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag NLY76_RS09055 Protein ID WP_171841422.1
Coordinates 1864127..1864462 (-) Length 112 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID A0A075SJ65
Locus tag NLY76_RS09060 Protein ID WP_024381089.1
Coordinates 1864455..1864742 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NLY76_RS09040 (NLY76_09040) 1860197..1860970 - 774 WP_044770177.1 nucleoside phosphorylase -
NLY76_RS09045 (NLY76_09045) 1860985..1861602 - 618 WP_015647409.1 serine O-acetyltransferase -
NLY76_RS09050 (NLY76_09050) 1861656..1863875 - 2220 WP_044770176.1 polyribonucleotide nucleotidyltransferase -
NLY76_RS09055 (NLY76_09055) 1864127..1864462 - 336 WP_171841422.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NLY76_RS09060 (NLY76_09060) 1864455..1864742 - 288 WP_024381089.1 XRE family transcriptional regulator Antitoxin
NLY76_RS09065 (NLY76_09065) 1865062..1865331 - 270 WP_002938849.1 30S ribosomal protein S15 -
NLY76_RS09070 (NLY76_09070) 1865536..1866813 - 1278 WP_024401941.1 solute carrier family 23 protein -
NLY76_RS09075 (NLY76_09075) 1867029..1867505 - 477 WP_044675947.1 hypothetical protein -
NLY76_RS09080 (NLY76_09080) 1867486..1867704 - 219 WP_044686159.1 helix-turn-helix transcriptional regulator -
NLY76_RS09085 (NLY76_09085) 1867847..1868356 - 510 WP_044686160.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(14-96)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 12818.91 Da        Isoelectric Point: 9.5061

>T250550 WP_171841422.1 NZ_CP100430:c1864462-1864127 [Streptococcus suis]
MDKYKVNLPLAIYEELADIRSYIREELKSPDAADKKIQELIAGLRSLEIFPERGFNVDERSKKGPLVPGQLTRGLPIKKD
YIAIYNIDEAQKVVNVRYLVASKSDYMRLFK

Download         Length: 336 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10686.33 Da        Isoelectric Point: 4.2626

>AT250550 WP_024381089.1 NZ_CP100430:c1864742-1864455 [Streptococcus suis]
MALTAEKKLINFQSEKSLVEEAKEVLASQNMTMTQALNLFLKNIVVTGEIGLKSEEELEKERLFAELQAEVMKNVAEMNA
GNYLSLDEMETKLFG

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A075SJ65

References