Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 1350297..1350842 Replicon chromosome
Accession NZ_CP100390
Organism Alkalimarinus sp. A2M4

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NKI27_RS06100 Protein ID WP_265049474.1
Coordinates 1350297..1350506 (-) Length 70 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NKI27_RS06105 Protein ID WP_265048796.1
Coordinates 1350570..1350842 (-) Length 91 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NKI27_RS06055 (NKI27_06055) 1345437..1345724 + 288 WP_265048787.1 type II toxin-antitoxin system RelE/ParE family toxin -
NKI27_RS06060 (NKI27_06060) 1345966..1346490 + 525 WP_265048788.1 HNH endonuclease -
NKI27_RS06065 (NKI27_06065) 1346612..1347160 + 549 WP_265048789.1 hypothetical protein -
NKI27_RS06070 (NKI27_06070) 1347406..1347660 + 255 WP_265048790.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
NKI27_RS06075 (NKI27_06075) 1347653..1347916 + 264 WP_265048791.1 Txe/YoeB family addiction module toxin -
NKI27_RS06080 (NKI27_06080) 1347980..1348645 + 666 WP_265048792.1 hypothetical protein -
NKI27_RS06085 (NKI27_06085) 1348714..1349589 + 876 WP_265048793.1 class A beta-lactamase -
NKI27_RS06090 (NKI27_06090) 1349655..1349957 - 303 WP_265048794.1 type II toxin-antitoxin system RelE/ParE family toxin -
NKI27_RS06095 (NKI27_06095) 1349957..1350196 - 240 WP_265048795.1 type II toxin-antitoxin system ParD family antitoxin -
NKI27_RS06100 (NKI27_06100) 1350297..1350506 - 210 WP_265049474.1 type II toxin-antitoxin system YafQ family toxin Toxin
NKI27_RS06105 (NKI27_06105) 1350570..1350842 - 273 WP_265048796.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
NKI27_RS06110 (NKI27_06110) 1351081..1351362 - 282 WP_265048797.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
NKI27_RS06115 (NKI27_06115) 1351610..1351927 + 318 WP_265048798.1 hypothetical protein -
NKI27_RS06120 (NKI27_06120) 1352207..1352995 + 789 WP_265048799.1 transporter substrate-binding domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(4-69)

Antitoxin

(3-83)


Sequences


Toxin        


Download         Length: 70 a.a.        Molecular weight: 7880.11 Da        Isoelectric Point: 6.8670

>T250518 WP_265049474.1 NZ_CP100390:c1350506-1350297 [Alkalimarinus sp. A2M4]
IPDVVEVGHVIKLLQLGETLPDKYVDHLLSGNWQGYRDCHVKPDLVLIYKVDNNSLKLARIGTHSELFR

Download         Length: 210 bp


Antitoxin


Download         Length: 91 a.a.        Molecular weight: 9773.14 Da        Isoelectric Point: 4.7627

>AT250518 WP_265048796.1 NZ_CP100390:c1350842-1350570 [Alkalimarinus sp. A2M4]
MKTEMLSTRIDHDTKLAFTNVCDDMGLSTSQALKLFAKAVINYGGIPFELKAKTPNTLTANAIEELESGNGTKAGTIEEL
FNHLDIDGLK

Download         Length: 273 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References