Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 1349655..1350196 Replicon chromosome
Accession NZ_CP100390
Organism Alkalimarinus sp. A2M4

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag NKI27_RS06090 Protein ID WP_265048794.1
Coordinates 1349655..1349957 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag NKI27_RS06095 Protein ID WP_265048795.1
Coordinates 1349957..1350196 (-) Length 80 a.a.

Genomic Context

NKI27_RS06050NKI27_RS06055NKI27_RS06060NKI27_RS06065NKI27_RS06070NKI27_RS06075NKI27_RS06080NKI27_RS06085NKI27_RS06115NKI27_RS06120NKI27_RS06090NKI27_RS06095NKI27_RS06100NKI27_RS06105NKI27_RS06110
Location: 1345174..1345440 (267 bp)
Type: Others
Protein ID: WP_265048786.1
Location: 1345437..1345724 (288 bp)
Type: Others
Protein ID: WP_265048787.1
Location: 1345966..1346490 (525 bp)
Type: Others
Protein ID: WP_265048788.1
Location: 1346612..1347160 (549 bp)
Type: Others
Protein ID: WP_265048789.1
Location: 1347406..1347660 (255 bp)
Type: Others
Protein ID: WP_265048790.1
Location: 1347653..1347916 (264 bp)
Type: Others
Protein ID: WP_265048791.1
Location: 1347980..1348645 (666 bp)
Type: Others
Protein ID: WP_265048792.1
Location: 1348714..1349589 (876 bp)
Type: Others
Protein ID: WP_265048793.1
Location: 1351610..1351927 (318 bp)
Type: Others
Protein ID: WP_265048798.1
Location: 1352207..1352995 (789 bp)
Type: Others
Protein ID: WP_265048799.1
Location: 1349655..1349957 (303 bp)
Type: Toxin
Protein ID: WP_265048794.1
Location: 1349957..1350196 (240 bp)
Type: Antitoxin
Protein ID: WP_265048795.1
Location: 1350297..1350506 (210 bp)
Type: Others
Protein ID: WP_265049474.1
Location: 1350570..1350842 (273 bp)
Type: Others
Protein ID: WP_265048796.1
Location: 1351081..1351362 (282 bp)
Type: Others
Protein ID: WP_265048797.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
NKI27_RS06050 (NKI27_06050)1345174..1345440+267WP_265048786.1transcriptional regulator-
NKI27_RS06055 (NKI27_06055)1345437..1345724+288WP_265048787.1type II toxin-antitoxin system RelE/ParE family toxin-
NKI27_RS06060 (NKI27_06060)1345966..1346490+525WP_265048788.1HNH endonuclease-
NKI27_RS06065 (NKI27_06065)1346612..1347160+549WP_265048789.1hypothetical protein-
NKI27_RS06070 (NKI27_06070)1347406..1347660+255WP_265048790.1type II toxin-antitoxin system prevent-host-death family antitoxin-
NKI27_RS06075 (NKI27_06075)1347653..1347916+264WP_265048791.1Txe/YoeB family addiction module toxin-
NKI27_RS06080 (NKI27_06080)1347980..1348645+666WP_265048792.1hypothetical protein-
NKI27_RS06085 (NKI27_06085)1348714..1349589+876WP_265048793.1class A beta-lactamase-
NKI27_RS06090 (NKI27_06090)1349655..1349957-303WP_265048794.1type II toxin-antitoxin system RelE/ParE family toxinToxin
NKI27_RS06095 (NKI27_06095)1349957..1350196-240WP_265048795.1type II toxin-antitoxin system ParD family antitoxinAntitoxin
NKI27_RS06100 (NKI27_06100)1350297..1350506-210WP_265049474.1type II toxin-antitoxin system YafQ family toxin-
NKI27_RS06105 (NKI27_06105)1350570..1350842-273WP_265048796.1type II toxin-antitoxin system RelB/DinJ family antitoxin-
NKI27_RS06110 (NKI27_06110)1351081..1351362-282WP_265048797.1type II toxin-antitoxin system Phd/YefM family antitoxin-
NKI27_RS06115 (NKI27_06115)1351610..1351927+318WP_265048798.1hypothetical protein-
NKI27_RS06120 (NKI27_06120)1352207..1352995+789WP_265048799.1transporter substrate-binding domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-92)

Antitoxin

Antitoxin ParD

(1-77)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11825.70 Da        Isoelectric Point: 10.5457

>T250516 WP_265048794.1 NZ_CP100390:c1349957-1349655 [Alkalimarinus sp. A2M4]
MGTFTLTTKARADLKSIAIYTQRKWGKEQRKIYIRQFDDTFHMLSKTPRVGTECDYIKTGYRKFPVTSHIVFYRGTSETS
IEIVRILHKNMDARERLVHP

Download         Length: 303 bp

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8886.91 Da        Isoelectric Point: 4.3566

>AT250516 WP_265048795.1 NZ_CP100390:c1350196-1349957 [Alkalimarinus sp. A2M4]
MPKNTSMTLGKHFDGFIANQINEGRFASASEVVRAALRMFEDNERKIAVLRQLLDEGEKSGTAEYSYESLMNELDDELG

Download         Length: 240 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References