Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/CC2985(antitoxin)
Location 78232..78765 Replicon chromosome
Accession NZ_CP100390
Organism Alkalimarinus sp. A2M4

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag NKI27_RS00355 Protein ID WP_265047716.1
Coordinates 78232..78528 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag NKI27_RS00360 Protein ID WP_265047717.1
Coordinates 78529..78765 (-) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NKI27_RS00330 (NKI27_00330) 73235..74638 + 1404 WP_265047711.1 MotA/TolQ/ExbB proton channel family protein -
NKI27_RS00335 (NKI27_00335) 74648..75184 + 537 WP_265047712.1 MotA/TolQ/ExbB proton channel family protein -
NKI27_RS00340 (NKI27_00340) 75218..75628 + 411 WP_265047713.1 biopolymer transporter ExbD -
NKI27_RS00345 (NKI27_00345) 75637..76359 + 723 WP_265047714.1 energy transducer TonB -
NKI27_RS00350 (NKI27_00350) 76356..78179 + 1824 WP_265047715.1 hypothetical protein -
NKI27_RS00355 (NKI27_00355) 78232..78528 - 297 WP_265047716.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NKI27_RS00360 (NKI27_00360) 78529..78765 - 237 WP_265047717.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
NKI27_RS00365 (NKI27_00365) 79267..80892 + 1626 WP_265047718.1 ATP-binding cassette domain-containing protein -
NKI27_RS00370 (NKI27_00370) 81062..81538 + 477 WP_265047719.1 DUF3124 domain-containing protein -
NKI27_RS00375 (NKI27_00375) 81535..82155 - 621 WP_265047720.1 MarC family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-91)

Antitoxin

Antitoxin ParD

(6-74)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11340.83 Da        Isoelectric Point: 4.4612

>T250511 WP_265047716.1 NZ_CP100390:c78528-78232 [Alkalimarinus sp. A2M4]
VSSFRLRPEAESDLETIWLYTEQNWGIEQAHAYIDGMVDIFQLLSNNPLMCPERSEFTPAVRIHHHAYHLVVFVLSDAGI
DVVRILHESMDIDTQLTF

Download         Length: 297 bp

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8996.15 Da        Isoelectric Point: 9.9627

>AT250511 WP_265047717.1 NZ_CP100390:c78765-78529 [Alkalimarinus sp. A2M4]
MATMNISLPDPMRDWVESQSKEGSYANNSDYVRDLIRKDQRQSEKRKAMQDAITKGIGSGEAKPFNKEAFKQRMQDKL

Download         Length: 237 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References