Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2845699..2845907 Replicon chromosome
Accession NZ_CP100388
Organism Enterobacter hormaechei subsp. steigerwaltii strain VKH10

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2845712..2845815 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2845699..2845907 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LZ581_RS13440 (LZ581_13440) 2841967..2843415 + 1449 WP_196344545.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
LZ581_RS13445 (LZ581_13445) 2843522..2843761 + 240 WP_003859885.1 YebV family protein -
LZ581_RS13450 (LZ581_13450) 2843796..2844440 - 645 Protein_2635 protein-serine/threonine phosphatase -
LZ581_RS13455 (LZ581_13455) 2844608..2845588 + 981 WP_017693251.1 DUF535 family protein -
LZ581_RS13460 (LZ581_13460) 2845634..2845831 + 198 WP_017693250.1 hypothetical protein -
- 2845699..2845907 + 209 - - Antitoxin
- 2845712..2845815 - 104 - - Toxin
LZ581_RS13465 (LZ581_13465) 2845956..2846294 - 339 WP_003859787.1 YebY family protein -
LZ581_RS13470 (LZ581_13470) 2846311..2847180 - 870 WP_017384341.1 copper homeostasis membrane protein CopD -
LZ581_RS13475 (LZ581_13475) 2847182..2847553 - 372 WP_023296802.1 CopC domain-containing protein YobA -
LZ581_RS13480 (LZ581_13480) 2847691..2847921 + 231 WP_003859784.1 DNA polymerase III subunit theta -
LZ581_RS13485 (LZ581_13485) 2848033..2848683 + 651 WP_017693248.1 nitrilase-related carbon-nitrogen hydrolase -
LZ581_RS13490 (LZ581_13490) 2848708..2849370 + 663 WP_015570288.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2836597..2851427 14830


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T250502 NZ_CP100388:c2845815-2845712 [Enterobacter hormaechei subsp. steigerwaltii]
GGCAAGGCGATTGAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 209 bp

>AT250502 NZ_CP100388:2845699-2845907 [Enterobacter hormaechei subsp. steigerwaltii]
TTTTCAAGCAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGC
TAAAAGTTGGCATTAATGCAGGCTCAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTCCACAGTA
AAAGTGGTCTGAAAAAAAGCGTCAGAACATCACTAAATGTGAAAACCGC

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References