Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-parD/RelE-RHH
Location 3516757..3517267 Replicon chromosome
Accession NZ_CP100351
Organism Desulfomicrobium sp. ZS1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NLA06_RS15765 Protein ID WP_256479470.1
Coordinates 3516989..3517267 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag NLA06_RS15760 Protein ID WP_254078817.1
Coordinates 3516757..3517002 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NLA06_RS15740 (NLA06_15740) 3513275..3514366 - 1092 WP_254078815.1 tetraacyldisaccharide 4'-kinase -
NLA06_RS15745 (NLA06_15745) 3514413..3515117 - 705 WP_015775326.1 Bax inhibitor-1/YccA family protein -
NLA06_RS15750 (NLA06_15750) 3515650..3515751 + 102 Protein_3084 prepilin-type N-terminal cleavage/methylation domain-containing protein -
NLA06_RS15755 (NLA06_15755) 3516286..3516531 + 246 WP_254078816.1 CopG family ribbon-helix-helix protein -
NLA06_RS15760 (NLA06_15760) 3516757..3517002 + 246 WP_254078817.1 CopG family ribbon-helix-helix protein Antitoxin
NLA06_RS15765 (NLA06_15765) 3516989..3517267 + 279 WP_256479470.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NLA06_RS15770 (NLA06_15770) 3517302..3518285 - 984 WP_254078818.1 transposase -
NLA06_RS15775 (NLA06_15775) 3518411..3518689 + 279 WP_254078819.1 DUF1778 domain-containing protein -
NLA06_RS15780 (NLA06_15780) 3518689..3519186 + 498 WP_254078820.1 GNAT family N-acetyltransferase -
NLA06_RS15785 (NLA06_15785) 3519235..3521637 + 2403 WP_254078821.1 acetate--CoA ligase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-90)

Antitoxin

Relaxosome protein TraY

(4-40)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10921.74 Da        Isoelectric Point: 10.7019

>T250494 WP_256479470.1 NZ_CP100351:3516989-3517267 [Desulfomicrobium sp. ZS1]
MSLTKVRWARNAIKDLERIRIFLEETADSEVMLFEAQRIWESCQRLRQFPESGRPGRIAFTREVVVSPYVIPYRVKKSVV
EILNIFHSAQKR

Download         Length: 279 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8930.91 Da        Isoelectric Point: 4.2259

>AT250494 WP_254078817.1 NZ_CP100351:3516757-3517002 [Desulfomicrobium sp. ZS1]
MSTVTARLSEETALKLSQLAQTTNRSKSFIVAQALEHFLDEQAWQVAQIQESLAQADEGKFASSIEVQEAFGKWGLTVES
D

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References