Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-parD/RHH(antitoxin)
Location 2689331..2689841 Replicon chromosome
Accession NZ_CP100351
Organism Desulfomicrobium sp. ZS1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NLA06_RS11865 Protein ID WP_254078140.1
Coordinates 2689331..2689561 (-) Length 77 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag NLA06_RS11870 Protein ID WP_254078141.1
Coordinates 2689599..2689841 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NLA06_RS11855 (NLA06_11855) 2686622..2686780 - 159 WP_254078139.1 hypothetical protein -
NLA06_RS11860 (NLA06_11860) 2686911..2688242 - 1332 WP_254080691.1 group II intron reverse transcriptase/maturase -
NLA06_RS11865 (NLA06_11865) 2689331..2689561 - 231 WP_254078140.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NLA06_RS11870 (NLA06_11870) 2689599..2689841 - 243 WP_254078141.1 ribbon-helix-helix protein, CopG family Antitoxin
NLA06_RS11875 (NLA06_11875) 2689952..2691559 - 1608 WP_254078142.1 DUF3369 domain-containing protein -
NLA06_RS11880 (NLA06_11880) 2691569..2693527 - 1959 WP_254078143.1 ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-73)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 77 a.a.        Molecular weight: 8831.19 Da        Isoelectric Point: 8.2657

>T250491 WP_254078140.1 NZ_CP100351:c2689561-2689331 [Desulfomicrobium sp. ZS1]
MSYIARDDAELAREIYCEVRRRASELSHFPESGCPGRVPGTRELVLARYPYVLPYRVRTGIVEILRVFHTSQKMDC

Download         Length: 231 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9022.07 Da        Isoelectric Point: 4.3449

>AT250491 WP_254078141.1 NZ_CP100351:c2689841-2689599 [Desulfomicrobium sp. ZS1]
MSTQISIRTSEDLILKFNALAKETDRSRAYLINQALEEYIAREAWQVAEIRKALQEADAGDFATDEEIAALDAKWGYRAG

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References