Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacT-ataR/DUF1778(antitoxin)
Location 1352979..1353757 Replicon chromosome
Accession NZ_CP100351
Organism Desulfomicrobium sp. ZS1

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag NLA06_RS06130 Protein ID WP_254080223.1
Coordinates 1352979..1353485 (-) Length 169 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag NLA06_RS06135 Protein ID WP_254080224.1
Coordinates 1353482..1353757 (-) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NLA06_RS06090 (NLA06_06090) 1348926..1349684 + 759 WP_254078279.1 IS21-like element helper ATPase IstB -
NLA06_RS06095 (NLA06_06095) 1349943..1350407 - 465 WP_254080216.1 helix-turn-helix transcriptional regulator -
NLA06_RS06100 (NLA06_06100) 1350485..1350700 + 216 WP_254080217.1 hypothetical protein -
NLA06_RS06105 (NLA06_06105) 1350697..1350960 + 264 WP_254080218.1 hypothetical protein -
NLA06_RS06110 (NLA06_06110) 1351118..1351405 + 288 WP_254080219.1 hypothetical protein -
NLA06_RS06115 (NLA06_06115) 1351468..1351617 + 150 WP_254080220.1 hypothetical protein -
NLA06_RS06120 (NLA06_06120) 1351741..1351989 + 249 WP_254080221.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
NLA06_RS06125 (NLA06_06125) 1351986..1352363 + 378 WP_254080222.1 type II toxin-antitoxin system VapC family toxin -
NLA06_RS06130 (NLA06_06130) 1352979..1353485 - 507 WP_254080223.1 GNAT family N-acetyltransferase Toxin
NLA06_RS06135 (NLA06_06135) 1353482..1353757 - 276 WP_254080224.1 DUF1778 domain-containing protein Antitoxin
NLA06_RS06140 (NLA06_06140) 1353873..1355390 - 1518 WP_254080225.1 B12-binding domain-containing radical SAM protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(46-145)

Antitoxin

Vibrio phage ICP1, Orf50

(7-74)


Sequences

Toxin        


Download         Length: 169 a.a.        Molecular weight: 18169.97 Da        Isoelectric Point: 9.5628

>T250489 WP_254080223.1 NZ_CP100351:c1353485-1352979 [Desulfomicrobium sp. ZS1]
VTESFSAPTPLTASHDVSSFSCAEPSLGDWLRHRAMKNQGSGATRTYVVCFGNTVVGYYSLAVGSIEHRFVAGSIKRNMP
EPIPVMILARLAVDRRYAGQCIGTGMLRDALLRTLQAAEIAGIRAMLVHALSEQAASFYRRRGFTASPFDPLVLFLALDH
VGIRLAGS

Download         Length: 507 bp

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 10163.36 Da        Isoelectric Point: 4.2558

>AT250489 WP_254080224.1 NZ_CP100351:c1353757-1353482 [Desulfomicrobium sp. ZS1]
MTATASINLRISDEEKALIDQAAQSLGKSRTAFILENTLRLAEEVVLDRTRFTLDSTQWEQFGAALDNPPSEEQLQGLAT
LFQAKAPWQQQ

Download         Length: 276 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References