Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 2227254..2227831 Replicon chromosome
Accession NZ_CP100350
Organism Gilvimarinus sp. DA14

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NHM04_RS09745 Protein ID WP_254263601.1
Coordinates 2227254..2227553 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NHM04_RS09750 Protein ID WP_254263602.1
Coordinates 2227550..2227831 (-) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NHM04_RS09725 (NHM04_09725) 2223203..2225206 + 2004 WP_254263597.1 protein-disulfide reductase DsbD family protein -
NHM04_RS09730 (NHM04_09730) 2225206..2225811 + 606 WP_254263598.1 thioredoxin family protein -
NHM04_RS09735 (NHM04_09735) 2225897..2226487 + 591 WP_254263599.1 DUF938 domain-containing protein -
NHM04_RS09740 (NHM04_09740) 2226484..2226900 + 417 WP_254263600.1 MAPEG family protein -
NHM04_RS09745 (NHM04_09745) 2227254..2227553 - 300 WP_254263601.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NHM04_RS09750 (NHM04_09750) 2227550..2227831 - 282 WP_254263602.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
NHM04_RS09755 (NHM04_09755) 2228106..2229503 + 1398 WP_254263603.1 methyl-accepting chemotaxis protein -
NHM04_RS09760 (NHM04_09760) 2229963..2230625 - 663 WP_254263604.1 hypothetical protein -
NHM04_RS09765 (NHM04_09765) 2230625..2231500 - 876 WP_254263605.1 nucleotidyltransferase -
NHM04_RS09770 (NHM04_09770) 2231579..2232355 - 777 WP_254263606.1 toll/interleukin-1 receptor domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(8-74)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11341.93 Da        Isoelectric Point: 4.5498

>T250487 WP_254263601.1 NZ_CP100350:c2227553-2227254 [Gilvimarinus sp. DA14]
MKVVWSPLALERVEDIARYIAEDKPDAAVEWVEGLFNTVERLSDFPQSGRVVPEVGGRRIREVMFGAYRIIYSVSDQIDI
LTVRRSSQLLRMSELGDEN

Download         Length: 300 bp

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10727.34 Da        Isoelectric Point: 7.2054

>AT250487 WP_254263602.1 NZ_CP100350:c2227831-2227550 [Gilvimarinus sp. DA14]
MSRVRVDEDIRPLSEFRAGVATFVKQIHETRRPMVLTQRGRGVAVLIDVQEYEKMQERLELLEEIYKAEEQIASGKGMSH
EDAKSRILGTLQK

Download         Length: 282 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References