Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | IV | Classification (family/domain) | abiEi-abiEii/AbiEii-AbiEi |
Location | 1323126..1324558 | Replicon | chromosome |
Accession | NZ_CP100334 | ||
Organism | Streptococcus suis strain STC83 |
Toxin (Protein)
Gene name | abiEi | Uniprot ID | G7SFZ4 |
Locus tag | NKZ67_RS06600 | Protein ID | WP_001030299.1 |
Coordinates | 1323713..1324558 (+) | Length | 282 a.a. |
Antitoxin (Protein)
Gene name | abiEii | Uniprot ID | G7SFZ3 |
Locus tag | NKZ67_RS06595 | Protein ID | WP_000037237.1 |
Coordinates | 1323126..1323716 (+) | Length | 197 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
NKZ67_RS06595 (NKZ67_06595) | 1323126..1323716 | + | 591 | WP_000037237.1 | type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein | Antitoxin |
NKZ67_RS06600 (NKZ67_06600) | 1323713..1324558 | + | 846 | WP_001030299.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin |
NKZ67_RS06605 (NKZ67_06605) | 1324621..1327422 | - | 2802 | WP_000656693.1 | phage tail tip lysozyme | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 282 a.a. Molecular weight: 32462.14 Da Isoelectric Point: 5.4404
>T250466 WP_001030299.1 NZ_CP100334:1323713-1324558 [Streptococcus suis]
MNKAKLTALCHKISKNTGLTFNSVMTYYFLEVILKKLSQSSYSNHYIFKGGFLLSNVIGVESRSTVDIDFLFHQITLSEE
TVKQQLKEILADSEEGISFVIQSITAIKESDDYGGYRATISCQLENIKQVIHLDIATGDVVTPQPITYDYKAIFDEDNFP
IIAYTIETILAEKLQTIYSRNFLNSRSKDFYDVYILSKLKKEDIDFIQLRNACQRTFSYRETELDFVKIIELLERFKSDP
IQNKQWQNYSKKYSYTKGISLADVLDEMIRLITVLISINSD
MNKAKLTALCHKISKNTGLTFNSVMTYYFLEVILKKLSQSSYSNHYIFKGGFLLSNVIGVESRSTVDIDFLFHQITLSEE
TVKQQLKEILADSEEGISFVIQSITAIKESDDYGGYRATISCQLENIKQVIHLDIATGDVVTPQPITYDYKAIFDEDNFP
IIAYTIETILAEKLQTIYSRNFLNSRSKDFYDVYILSKLKKEDIDFIQLRNACQRTFSYRETELDFVKIIELLERFKSDP
IQNKQWQNYSKKYSYTKGISLADVLDEMIRLITVLISINSD
Download Length: 846 bp
Antitoxin
Download Length: 197 a.a. Molecular weight: 23056.59 Da Isoelectric Point: 7.8056
>AT250466 WP_000037237.1 NZ_CP100334:1323126-1323716 [Streptococcus suis]
MSKKEILLDFIEKNNGIVTNKDCKALGIPTIYLTRLEKEGIIFRVEKGIFLTQNGDYDEYYFFQYRFPKAIFSYISALYL
QQFTDEIPQYFDVTVPRGYRFNTPPANLNIHFVSKEYSELGMTTVPTPLGNNVRVYDFERIICDFVIHREKIDSELFVKT
LQSYGNYPKKNLAKLYEYATKMNTLEKVKQTLEVLI
MSKKEILLDFIEKNNGIVTNKDCKALGIPTIYLTRLEKEGIIFRVEKGIFLTQNGDYDEYYFFQYRFPKAIFSYISALYL
QQFTDEIPQYFDVTVPRGYRFNTPPANLNIHFVSKEYSELGMTTVPTPLGNNVRVYDFERIICDFVIHREKIDSELFVKT
LQSYGNYPKKNLAKLYEYATKMNTLEKVKQTLEVLI
Download Length: 591 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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