Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) slvAT/RES(toxin)
Location 369952..370859 Replicon plasmid pMESCI01
Accession NC_014918
Organism Mesorhizobium ciceri biovar biserrulae WSM1271

Toxin (Protein)


Gene name slvT Uniprot ID E8TNW2
Locus tag MESCI_RS31940 Protein ID WP_013525336.1
Coordinates 369952..370476 (-) Length 175 a.a.

Antitoxin (Protein)


Gene name slvA Uniprot ID E8TNW3
Locus tag MESCI_RS31945 Protein ID WP_013525337.1
Coordinates 370473..370859 (-) Length 129 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MESCI_RS31915 366010..366399 + 390 WP_013525331.1 DUF2384 domain-containing protein -
MESCI_RS31920 366396..366914 + 519 WP_013525332.1 RES family NAD+ phosphorylase -
MESCI_RS31925 366938..368110 - 1173 WP_013525333.1 site-specific integrase -
MESCI_RS31930 368235..369188 + 954 WP_013525334.1 DUF1403 family protein -
MESCI_RS31935 369191..369913 + 723 WP_013525335.1 SMC-Scp complex subunit ScpB -
MESCI_RS31940 369952..370476 - 525 WP_013525336.1 RES domain-containing protein Toxin
MESCI_RS31945 370473..370859 - 387 WP_013525337.1 hypothetical protein Antitoxin
MESCI_RS31950 371124..372045 - 922 Protein_359 type I restriction-modification system subunit M -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..425539 425539


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(12-169)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 175 a.a.        Molecular weight: 19063.53 Da        Isoelectric Point: 6.4832

>T25046 WP_013525336.1 NC_014918:c370476-369952 [Mesorhizobium ciceri biovar biserrulae WSM1271]
VKVTRVGPDEIFHRYLTPKWAFLPTSGGGAAIDGGRFNRPGVEAVYLSRAPQTALEEYKQGASITPPATLAAYKITLSEI
ADLSQGFDPNVWDSAWNEWDCAWRQIARIDSKIPSSWKLADLVVTTGLRGILFPSLRHAGGTNLVIFPANLVDGDKVAVH
DPDHRLPTDQSSWP

Download         Length: 525 bp

>T25046 NC_014918:c370476-369952 [Mesorhizobium ciceri biovar biserrulae WSM1271]
GTGAAGGTCACCCGCGTCGGGCCGGACGAGATCTTCCATCGCTATCTGACACCCAAATGGGCCTTCCTGCCCACCAGTGG
TGGGGGCGCGGCGATCGATGGCGGGCGCTTCAATCGGCCCGGCGTCGAAGCCGTTTACCTGTCCCGCGCGCCTCAGACAG
CGTTGGAGGAATACAAGCAGGGTGCCAGCATCACCCCGCCCGCCACCCTTGCCGCCTACAAGATCACGCTTTCCGAGATC
GCCGATCTTTCTCAGGGGTTCGACCCGAATGTTTGGGATAGTGCCTGGAACGAATGGGATTGTGCCTGGCGCCAGATCGC
TCGCATCGACAGCAAGATACCGTCATCGTGGAAGCTTGCGGACCTGGTCGTTACGACCGGGCTTCGCGGTATTCTGTTTC
CGTCGCTGCGTCACGCCGGCGGCACCAATCTGGTGATCTTTCCGGCCAATCTTGTCGACGGTGATAAGGTCGCGGTTCAC
GATCCCGATCACCGGCTACCGACCGATCAGTCATCATGGCCCTGA

Antitoxin


Download         Length: 129 a.a.        Molecular weight: 14030.97 Da        Isoelectric Point: 9.8613

>AT25046 WP_013525337.1 NC_014918:c370859-370473 [Mesorhizobium ciceri biovar biserrulae WSM1271]
MTHAQLAQSKVVSGFVDSLQEPRTPYISPKRLSQALGVKVANLAQLTGVHRNTLRNPSSERLQGRMREMVKVISAATELT
GDVDKAIYWYRNEPIADYGHRTAAELVAGGQVEAVLAFIRDLENGARG

Download         Length: 387 bp

>AT25046 NC_014918:c370859-370473 [Mesorhizobium ciceri biovar biserrulae WSM1271]
ATGACCCACGCACAGCTCGCACAATCGAAAGTGGTCTCAGGTTTTGTCGACAGCCTGCAGGAGCCGCGCACGCCTTATAT
CTCGCCGAAGCGCCTGTCGCAGGCGCTGGGCGTGAAGGTGGCCAACTTGGCGCAGTTGACCGGCGTCCACCGCAACACGC
TCCGTAACCCGTCGTCGGAGCGACTGCAGGGTCGGATGCGCGAGATGGTGAAGGTGATTTCGGCCGCAACGGAACTCACC
GGCGACGTCGACAAGGCGATCTACTGGTATCGCAATGAGCCGATCGCCGACTATGGCCATCGCACGGCGGCCGAACTCGT
CGCGGGCGGCCAGGTCGAAGCAGTGCTGGCCTTCATCCGGGATCTCGAGAACGGGGCGCGCGGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB E8TNW2

Antitoxin

Source ID Structure
AlphaFold DB A0A436N5N0

References