Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1925053..1925198 Replicon chromosome
Accession NZ_CP100312
Organism Klebsiella pneumoniae strain 1020

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1925089..1925191 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1925053..1925198 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NKX97_RS09310 1920183..1922243 + 2061 WP_004151449.1 oligopeptidase B -
NKX97_RS09315 1922247..1922906 - 660 WP_002911407.1 exodeoxyribonuclease X -
NKX97_RS09320 1922985..1923215 - 231 WP_002911406.1 DNA polymerase III subunit theta -
NKX97_RS09325 1923328..1923702 + 375 WP_004151448.1 CopC domain-containing protein YobA -
NKX97_RS09330 1923706..1924575 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
NKX97_RS09335 1924592..1924930 + 339 WP_004189269.1 YebY family protein -
- 1925053..1925198 - 146 - - Antitoxin
- 1925089..1925191 + 103 - - Toxin
NKX97_RS09340 1925565..1925708 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
NKX97_RS09345 1925813..1926781 - 969 WP_004151446.1 VirK/YbjX family protein -
NKX97_RS09350 1926938..1927591 + 654 WP_004189273.1 protein-serine/threonine phosphatase -
NKX97_RS09355 1927588..1927779 - 192 WP_002911395.1 YebW family protein -
NKX97_RS09360 1927877..1928116 - 240 WP_002911393.1 YebV family protein -
NKX97_RS09365 1928232..1929665 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T250426 NZ_CP100312:1925089-1925191 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT250426 NZ_CP100312:c1925198-1925053 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References