Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1925169..1925314 Replicon chromosome
Accession NZ_CP100308
Organism Klebsiella pneumoniae strain 1021

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1925205..1925307 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1925169..1925314 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NKY02_RS09310 1920299..1922359 + 2061 WP_004151449.1 oligopeptidase B -
NKY02_RS09315 1922363..1923022 - 660 WP_002911407.1 exodeoxyribonuclease X -
NKY02_RS09320 1923101..1923331 - 231 WP_002911406.1 DNA polymerase III subunit theta -
NKY02_RS09325 1923444..1923818 + 375 WP_004151448.1 CopC domain-containing protein YobA -
NKY02_RS09330 1923822..1924691 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
NKY02_RS09335 1924708..1925046 + 339 WP_004189269.1 YebY family protein -
- 1925169..1925314 - 146 - - Antitoxin
- 1925205..1925307 + 103 - - Toxin
NKY02_RS09340 1925681..1925824 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
NKY02_RS09345 1925929..1926897 - 969 WP_004151446.1 VirK/YbjX family protein -
NKY02_RS09350 1927054..1927707 + 654 WP_004189273.1 protein-serine/threonine phosphatase -
NKY02_RS09355 1927704..1927895 - 192 WP_002911395.1 YebW family protein -
NKY02_RS09360 1927993..1928232 - 240 WP_002911393.1 YebV family protein -
NKY02_RS09365 1928348..1929781 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T250409 NZ_CP100308:1925205-1925307 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT250409 NZ_CP100308:c1925314-1925169 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References