Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 2787958..2788611 Replicon chromosome
Accession NZ_CP100305
Organism Acinetobacter baumannii strain KBN10P05679

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag NIK71_RS13550 Protein ID WP_000607077.1
Coordinates 2787958..2788347 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag NIK71_RS13555 Protein ID WP_001288210.1
Coordinates 2788354..2788611 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NIK71_RS13535 (NIK71_13535) 2783076..2785271 - 2196 WP_001158906.1 TRAP transporter large permease subunit -
NIK71_RS13540 (NIK71_13540) 2785459..2786025 - 567 WP_000651538.1 rhombosortase -
NIK71_RS13545 (NIK71_13545) 2786103..2787188 - 1086 WP_000049106.1 hypothetical protein -
NIK71_RS13550 (NIK71_13550) 2787958..2788347 - 390 WP_000607077.1 membrane protein Toxin
NIK71_RS13555 (NIK71_13555) 2788354..2788611 - 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
NIK71_RS13560 (NIK71_13560) 2788799..2789971 + 1173 WP_001190542.1 acyl-CoA dehydrogenase family protein -
NIK71_RS13565 (NIK71_13565) 2790020..2791510 - 1491 WP_000415125.1 NAD(P)/FAD-dependent oxidoreductase -
NIK71_RS13570 (NIK71_13570) 2791692..2792069 - 378 WP_001216380.1 50S ribosomal protein L17 -
NIK71_RS13575 (NIK71_13575) 2792088..2793095 - 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15552.88 Da        Isoelectric Point: 10.4313

>T250402 WP_000607077.1 NZ_CP100305:c2788347-2787958 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT250402 WP_001288210.1 NZ_CP100305:c2788611-2788354 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References