Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 2787958..2788611 Replicon chromosome
Accession NZ_CP100305
Organism Acinetobacter baumannii strain KBN10P05679

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag NIK71_RS13550 Protein ID WP_000607077.1
Coordinates 2787958..2788347 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag NIK71_RS13555 Protein ID WP_001288210.1
Coordinates 2788354..2788611 (-) Length 86 a.a.

Genomic Context

NIK71_RS13560NIK71_RS13535NIK71_RS13540NIK71_RS13545NIK71_RS13550NIK71_RS13555NIK71_RS13565NIK71_RS13570NIK71_RS13575
Location: 2788799..2789971 (1173 bp)
Type: Others
Protein ID: WP_001190542.1
Location: 2783076..2785271 (2196 bp)
Type: Others
Protein ID: WP_001158906.1
Location: 2785459..2786025 (567 bp)
Type: Others
Protein ID: WP_000651538.1
Location: 2786103..2787188 (1086 bp)
Type: Others
Protein ID: WP_000049106.1
Location: 2787958..2788347 (390 bp)
Type: Toxin
Protein ID: WP_000607077.1
Location: 2788354..2788611 (258 bp)
Type: Antitoxin
Protein ID: WP_001288210.1
Location: 2790020..2791510 (1491 bp)
Type: Others
Protein ID: WP_000415125.1
Location: 2791692..2792069 (378 bp)
Type: Others
Protein ID: WP_001216380.1
Location: 2792088..2793095 (1008 bp)
Type: Others
Protein ID: WP_000198631.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
NIK71_RS13535 (NIK71_13535)2783076..2785271-2196WP_001158906.1TRAP transporter large permease subunit-
NIK71_RS13540 (NIK71_13540)2785459..2786025-567WP_000651538.1rhombosortase-
NIK71_RS13545 (NIK71_13545)2786103..2787188-1086WP_000049106.1hypothetical protein-
NIK71_RS13550 (NIK71_13550)2787958..2788347-390WP_000607077.1membrane proteinToxin
NIK71_RS13555 (NIK71_13555)2788354..2788611-258WP_001288210.1succinate dehydrogenase assembly factor 2Antitoxin
NIK71_RS13560 (NIK71_13560)2788799..2789971+1173WP_001190542.1acyl-CoA dehydrogenase family protein-
NIK71_RS13565 (NIK71_13565)2790020..2791510-1491WP_000415125.1NAD(P)/FAD-dependent oxidoreductase-
NIK71_RS13570 (NIK71_13570)2791692..2792069-378WP_001216380.150S ribosomal protein L17-
NIK71_RS13575 (NIK71_13575)2792088..2793095-1008WP_000198631.1DNA-directed RNA polymerase subunit alpha-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15552.88 Da        Isoelectric Point: 10.4313

>T250402 WP_000607077.1 NZ_CP100305:c2788347-2787958 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT250402 WP_001288210.1 NZ_CP100305:c2788611-2788354 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A7U4BQM7

References