Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 1103704..1104479 Replicon chromosome
Accession NZ_CP100297
Organism Burkholderia glumae strain SL-2395S

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag NIX96_RS22720 Protein ID WP_017423245.1
Coordinates 1103982..1104479 (+) Length 166 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag NIX96_RS22715 Protein ID WP_017423246.1
Coordinates 1103704..1103985 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NIX96_RS22705 1101686..1102123 + 438 WP_159372664.1 SMI1/KNR4 family protein -
NIX96_RS22710 1102247..1103484 + 1238 WP_088499505.1 IS3-like element IS1416 family transposase -
NIX96_RS22715 1103704..1103985 + 282 WP_017423246.1 DUF1778 domain-containing protein Antitoxin
NIX96_RS22720 1103982..1104479 + 498 WP_017423245.1 GNAT family N-acetyltransferase Toxin
NIX96_RS22725 1104560..1105057 + 498 WP_251107809.1 ProQ/FINO family protein -
NIX96_RS22730 1105473..1106078 + 606 Protein_986 RHS repeat-associated core domain-containing protein -
NIX96_RS22735 1106214..1106456 + 243 WP_257757996.1 TIGR02269 family lipoprotein -
NIX96_RS22740 1106473..1106757 + 285 WP_153478924.1 hypothetical protein -
NIX96_RS22745 1106880..1107425 + 546 Protein_989 IS3 family transposase -
NIX96_RS22750 1107497..1107592 + 96 Protein_990 IS5/IS1182 family transposase -
NIX96_RS22755 1107678..1109027 - 1350 WP_017424540.1 allantoin permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - fliC 1083938..1119110 35172
- inside IScluster/Tn - - 1102247..1107449 5202


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(44-144)

Antitoxin

Vibrio phage ICP1, Orf50

(10-84)


Sequences

Toxin        


Download         Length: 166 a.a.        Molecular weight: 17606.19 Da        Isoelectric Point: 9.6894

>T250392 WP_017423245.1 NZ_CP100297:1103982-1104479 [Burkholderia glumae]
MTGWRAPEPLSDAHGLDDFDSGVASLDTWLKRRALANQRSGASRTFVATRDGRVGAYYALASGAVTLEVAPGRFRRNMPD
PIPVVVLGRLAVDRAHQGIGVGRALVRDAGLRVLHAAAAIGIRSLIVHALSDSAKAFYERVGFEASPLDPMLLLITLADL
EHALS

Download         Length: 498 bp

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10082.37 Da        Isoelectric Point: 7.0104

>AT250392 WP_017423246.1 NZ_CP100297:1103704-1103985 [Burkholderia glumae]
MASTTPRDTLNLRIRPDDRSLIDRAAAAAHKTRTDFVLDAARAAAEQTLLDQVVLSAEPQAYAAFLARLDAPAQPNAALR
QTMQTRAPWDPAA

Download         Length: 282 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References