Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 1055563..1056338 Replicon chromosome
Accession NZ_CP100292
Organism Burkholderia glumae strain R2

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag NIX97_RS21825 Protein ID WP_017423245.1
Coordinates 1055841..1056338 (+) Length 166 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag NIX97_RS21820 Protein ID WP_017423246.1
Coordinates 1055563..1055844 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NIX97_RS21810 1053545..1053982 + 438 WP_159372664.1 SMI1/KNR4 family protein -
NIX97_RS21815 1054106..1055343 + 1238 WP_088499505.1 IS3-like element IS1416 family transposase -
NIX97_RS21820 1055563..1055844 + 282 WP_017423246.1 DUF1778 domain-containing protein Antitoxin
NIX97_RS21825 1055841..1056338 + 498 WP_017423245.1 GNAT family N-acetyltransferase Toxin
NIX97_RS21830 1056419..1056916 + 498 WP_251107809.1 ProQ/FINO family protein -
NIX97_RS21835 1057332..1057937 + 606 Protein_924 RHS repeat-associated core domain-containing protein -
NIX97_RS21840 1058073..1058315 + 243 WP_257757996.1 TIGR02269 family lipoprotein -
NIX97_RS21845 1058332..1058616 + 285 WP_153478924.1 hypothetical protein -
NIX97_RS21850 1058739..1059284 + 546 Protein_927 IS3 family transposase -
NIX97_RS21855 1059356..1059451 + 96 Protein_928 IS5/IS1182 family transposase -
NIX97_RS21860 1059537..1060886 - 1350 WP_017424540.1 allantoin permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - fliC 1037489..1070969 33480
- inside IScluster/Tn - - 1054106..1059308 5202


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(44-144)

Antitoxin

Vibrio phage ICP1, Orf50

(10-84)


Sequences

Toxin        


Download         Length: 166 a.a.        Molecular weight: 17606.19 Da        Isoelectric Point: 9.6894

>T250387 WP_017423245.1 NZ_CP100292:1055841-1056338 [Burkholderia glumae]
MTGWRAPEPLSDAHGLDDFDSGVASLDTWLKRRALANQRSGASRTFVATRDGRVGAYYALASGAVTLEVAPGRFRRNMPD
PIPVVVLGRLAVDRAHQGIGVGRALVRDAGLRVLHAAAAIGIRSLIVHALSDSAKAFYERVGFEASPLDPMLLLITLADL
EHALS

Download         Length: 498 bp

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10082.37 Da        Isoelectric Point: 7.0104

>AT250387 WP_017423246.1 NZ_CP100292:1055563-1055844 [Burkholderia glumae]
MASTTPRDTLNLRIRPDDRSLIDRAAAAAHKTRTDFVLDAARAAAEQTLLDQVVLSAEPQAYAAFLARLDAPAQPNAALR
QTMQTRAPWDPAA

Download         Length: 282 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References