Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | slvAT/RES(toxin) |
| Location | 5208..6154 | Replicon | plasmid p48s4p |
| Accession | NZ_CP100290 | ||
| Organism | Burkholderia glumae strain BGR48S | ||
Toxin (Protein)
| Gene name | slvT | Uniprot ID | - |
| Locus tag | NIX85_RS30335 | Protein ID | WP_257820654.1 |
| Coordinates | 5621..6154 (+) | Length | 178 a.a. |
Antitoxin (Protein)
| Gene name | slvA | Uniprot ID | C5AN90 |
| Locus tag | NIX85_RS30330 | Protein ID | WP_012732708.1 |
| Coordinates | 5208..5624 (+) | Length | 139 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NIX85_RS30315 | 1251..2225 | + | 975 | WP_257806992.1 | ParB/RepB/Spo0J family partition protein | - |
| NIX85_RS30320 | 2555..3886 | + | 1332 | WP_257820652.1 | helix-turn-helix domain-containing protein | - |
| NIX85_RS30325 | 4876..5061 | + | 186 | WP_153479281.1 | hypothetical protein | - |
| NIX85_RS30330 | 5208..5624 | + | 417 | WP_012732708.1 | DUF2384 domain-containing protein | Antitoxin |
| NIX85_RS30335 | 5621..6154 | + | 534 | WP_257820654.1 | RES family NAD+ phosphorylase | Toxin |
| NIX85_RS30340 | 6324..6512 | + | 189 | WP_257820656.1 | hypothetical protein | - |
| NIX85_RS30345 | 6599..7537 | - | 939 | WP_257820657.1 | hypothetical protein | - |
| NIX85_RS30350 | 7948..8220 | + | 273 | WP_257820659.1 | integrase | - |
| NIX85_RS30355 | 8234..8557 | + | 324 | WP_257820661.1 | hypothetical protein | - |
| NIX85_RS30360 | 8790..9878 | + | 1089 | WP_257820732.1 | hypothetical protein | - |
| NIX85_RS30365 | 9930..10085 | + | 156 | WP_257807019.1 | hypothetical protein | - |
| NIX85_RS30370 | 10245..10625 | + | 381 | WP_257807021.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | - | 1..100711 | 100711 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 178 a.a. Molecular weight: 19061.51 Da Isoelectric Point: 4.7118
>T250383 WP_257820654.1 NZ_CP100290:5621-6154 [Burkholderia glumae]
MILTPLQDITAYRMHVPKWAVAPTSGAGAAKAGGRANRIGTPALYLALEASTAVAEYQQLSPLLPPGTLVSYRVTATPVV
DFTGGYRADLWPPLWESFFCDWRHDWFNARIEPPSWVLGDEAIASGAKGILFRSTQAAGGTNLVLFVDQLGEGDRVDVHD
PAGALPRDQASWADSPE
MILTPLQDITAYRMHVPKWAVAPTSGAGAAKAGGRANRIGTPALYLALEASTAVAEYQQLSPLLPPGTLVSYRVTATPVV
DFTGGYRADLWPPLWESFFCDWRHDWFNARIEPPSWVLGDEAIASGAKGILFRSTQAAGGTNLVLFVDQLGEGDRVDVHD
PAGALPRDQASWADSPE
Download Length: 534 bp
Antitoxin
Download Length: 139 a.a. Molecular weight: 14709.55 Da Isoelectric Point: 6.4664
>AT250383 WP_012732708.1 NZ_CP100290:5208-5624 [Burkholderia glumae]
MSTLAAARAPAGGPALANFDAFLSALREPDTAAPVLSARRYVAALNIDLQTLADQAHVHRNTVARAPQSASVQQFLREAI
RVIRAATDLSGDVQRALFWYRNEPLAVFDYQTAETLVSAGRADDVVRYVASLEAGAAG
MSTLAAARAPAGGPALANFDAFLSALREPDTAAPVLSARRYVAALNIDLQTLADQAHVHRNTVARAPQSASVQQFLREAI
RVIRAATDLSGDVQRALFWYRNEPLAVFDYQTAETLVSAGRADDVVRYVASLEAGAAG
Download Length: 417 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|