Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 56697..57469 Replicon plasmid p48s3p
Accession NZ_CP100289
Organism Burkholderia glumae strain BGR48S

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag NIX85_RS30025 Protein ID WP_257820497.1
Coordinates 56697..57191 (-) Length 165 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag NIX85_RS30030 Protein ID WP_039204507.1
Coordinates 57188..57469 (-) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NIX85_RS30000 52900..53355 + 456 WP_012732735.1 transposase -
NIX85_RS30005 53355..53708 + 354 WP_012732734.1 IS66 family insertion sequence element accessory protein TnpB -
NIX85_RS30010 53808..55394 + 1587 WP_173941343.1 IS66 family transposase -
NIX85_RS30015 55391..56044 + 654 WP_257820570.1 hypothetical protein -
NIX85_RS30020 56134..56604 - 471 WP_080763678.1 ProQ/FINO family protein -
NIX85_RS30025 56697..57191 - 495 WP_257820497.1 GNAT family N-acetyltransferase Toxin
NIX85_RS30030 57188..57469 - 282 WP_039204507.1 DUF1778 domain-containing protein Antitoxin
NIX85_RS30040 58544..59497 - 954 WP_039205200.1 hypothetical protein -
NIX85_RS30045 60113..60930 + 818 WP_257758106.1 IS5-like element ISBugl2 family transposase -
NIX85_RS30050 61055..62074 + 1020 WP_252836473.1 IS110 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..112798 112798
- flank IS/Tn - - 61055..62074 1019


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(44-144)

Antitoxin

Vibrio phage ICP1, Orf50

(5-91)


Sequences

Toxin        


Download         Length: 165 a.a.        Molecular weight: 17515.08 Da        Isoelectric Point: 9.6522

>T250382 WP_257820497.1 NZ_CP100289:c57191-56697 [Burkholderia glumae]
MTGWRAPEPLSDAHGLDDFDSGVASLDKWLKRRALANQQSGASRTFVATRDGRVGAYYALASGVVTPEVAPGRFRRNMPD
PIPVVVLGRLAVDRAHQGNGVGRALVRDAGLRVLHAAAAIGIRGLIVHALTDSAKAFYERVGFEASPIDPMLLLITLADL
EHAL

Download         Length: 495 bp

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10170.43 Da        Isoelectric Point: 5.7881

>AT250382 WP_039204507.1 NZ_CP100289:c57469-57188 [Burkholderia glumae]
MTSTTPRDTLNLRIRPDDRSLIDRAAAAAHKTRTDFVLDAARAAAEQTLLDQVVLSAEPQAYAAFLARLDAPAQPNEALR
QTMQTRAPWDPAA

Download         Length: 282 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References