Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpSB/PRK09812-ChpS
Location 184413..185008 Replicon plasmid p79s1p
Accession NZ_CP100264
Organism Burkholderia glumae strain BGR79S

Toxin (Protein)


Gene name chpB Uniprot ID C5AN78
Locus tag NIX86_RS30020 Protein ID WP_012734107.1
Coordinates 184413..184763 (-) Length 117 a.a.

Antitoxin (Protein)


Gene name chpS Uniprot ID C5AN79
Locus tag NIX86_RS30025 Protein ID WP_012734108.1
Coordinates 184757..185008 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NIX86_RS29995 179635..180381 - 747 WP_232252306.1 energy transducer TonB -
NIX86_RS30000 180413..182788 - 2376 WP_232252305.1 TonB-dependent receptor -
NIX86_RS30005 183102..183566 - 465 WP_012734106.1 Lrp/AsnC family transcriptional regulator -
NIX86_RS30010 183789..184010 - 222 WP_017433768.1 hypothetical protein -
NIX86_RS30015 184160..184354 - 195 WP_124837685.1 hypothetical protein -
NIX86_RS30020 184413..184763 - 351 WP_012734107.1 type II toxin-antitoxin system ChpB family toxin Toxin
NIX86_RS30025 184757..185008 - 252 WP_012734108.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
NIX86_RS30030 185271..185678 - 408 WP_230674618.1 hypothetical protein -
NIX86_RS30035 185781..187616 - 1836 WP_124837684.1 site-specific integrase -
NIX86_RS30040 187619..187960 - 342 WP_012732710.1 hypothetical protein -
NIX86_RS30045 188017..188262 - 246 WP_127913916.1 hypothetical protein -
NIX86_RS30050 188259..188501 - 243 WP_124837682.1 hypothetical protein -
NIX86_RS30055 188515..188799 - 285 WP_017432347.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..189346 189346


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(8-114)

Antitoxin

Antitoxin PemI-like

(1-83)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12389.37 Da        Isoelectric Point: 8.8909

>T250363 WP_012734107.1 NZ_CP100264:c184763-184413 [Burkholderia glumae]
MVKRVKFERGDIVRVSLSPTVGREQQGDFRPALVLSPAAFNALGVALVAPITQGGEFARFAGFAVPLSGSGTETQGVALV
NMVRMLDLEGRGARKIERAPVEVVEDALARLQTIIE

Download         Length: 351 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 8940.31 Da        Isoelectric Point: 6.2420

>AT250363 WP_012734108.1 NZ_CP100264:c185008-184757 [Burkholderia glumae]
MELKIQKWGNSAAVRLPSVLLEQINASVGGSLNADVRPDGVLLTPARRKYALDDLVAQCDTKAPVPADMAAWGEIKPVGR
EAW

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A246MF70

Antitoxin

Source ID Structure
AlphaFold DB A0A246MFN5

References