Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 106819..107591 Replicon plasmid p28s1p
Accession NZ_CP100246
Organism Burkholderia glumae strain BGR28S

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag NIX71_RS29915 Protein ID WP_039204503.1
Coordinates 107097..107591 (+) Length 165 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag NIX71_RS29910 Protein ID WP_039204507.1
Coordinates 106819..107100 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NIX71_RS29900 104791..105744 + 954 WP_039205200.1 hypothetical protein -
NIX71_RS29905 105797..106602 + 806 WP_257820499.1 IS5 family transposase -
NIX71_RS29910 106819..107100 + 282 WP_039204507.1 DUF1778 domain-containing protein Antitoxin
NIX71_RS29915 107097..107591 + 495 WP_039204503.1 GNAT family N-acetyltransferase Toxin
NIX71_RS29920 107684..108154 + 471 WP_080763678.1 ProQ/FINO family protein -
NIX71_RS29925 108244..111165 - 2922 WP_257758109.1 MobF family relaxase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..169201 169201


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(44-144)

Antitoxin

Vibrio phage ICP1, Orf50

(5-91)


Sequences

Toxin        


Download         Length: 165 a.a.        Molecular weight: 17543.14 Da        Isoelectric Point: 10.0778

>T250348 WP_039204503.1 NZ_CP100246:107097-107591 [Burkholderia glumae]
MTGWRAPEPLSDAHGLDDFDSGVASLDKWLKRRALANQRSGASRTFVATRDGRVGAYYALASGVVTPEVAPGRFRRNMPD
PIPVVVLGRLAVDRAHQGNGVGRALVRDAGLRVLHAAAAIGIRGLIVHALTDSAKAFYERVGFEASPIDPMLLLITLADL
EHAL

Download         Length: 495 bp

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10170.43 Da        Isoelectric Point: 5.7881

>AT250348 WP_039204507.1 NZ_CP100246:106819-107100 [Burkholderia glumae]
MTSTTPRDTLNLRIRPDDRSLIDRAAAAAHKTRTDFVLDAARAAAEQTLLDQVVLSAEPQAYAAFLARLDAPAQPNEALR
QTMQTRAPWDPAA

Download         Length: 282 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References