Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 58854..59626 Replicon plasmid p22s3p
Accession NZ_CP100242
Organism Burkholderia glumae strain BGR22S

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag NIX74_RS31540 Protein ID WP_257819017.1
Coordinates 59132..59626 (+) Length 165 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag NIX74_RS31535 Protein ID WP_257819015.1
Coordinates 58854..59135 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NIX74_RS31525 57526..57852 + 327 WP_257819108.1 hypothetical protein -
NIX74_RS31530 58161..58577 + 417 WP_257819110.1 hypothetical protein -
NIX74_RS31535 58854..59135 + 282 WP_257819015.1 DUF1778 domain-containing protein Antitoxin
NIX74_RS31540 59132..59626 + 495 WP_257819017.1 GNAT family N-acetyltransferase Toxin
NIX74_RS31545 59718..60191 + 474 WP_257819019.1 ProQ/FinO family protein -
NIX74_RS31550 60505..62061 - 1557 WP_012732752.1 IS66 family transposase -
NIX74_RS31555 62093..62443 - 351 WP_012732753.1 IS66 family insertion sequence element accessory protein TnpB -
NIX74_RS31560 62419..62922 - 504 WP_012732754.1 transposase -
NIX74_RS31565 62943..63134 - 192 WP_257819021.1 transposase -
NIX74_RS31570 63256..63627 - 372 WP_257819023.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..116826 116826


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(44-144)

Antitoxin

Vibrio phage ICP1, Orf50

(5-91)


Sequences

Toxin        


Download         Length: 165 a.a.        Molecular weight: 17546.10 Da        Isoelectric Point: 9.6894

>T250345 WP_257819017.1 NZ_CP100242:59132-59626 [Burkholderia glumae]
MTGWRAPEPLSDAHGLDDFDSGVASLDTWLKRRALANQRSGASRTFVATRDGRVGAYYALASGAVTPEVAPGRFRRNMPD
PIPVVVLGRLAVDRVHQGNGVGRALVRDAGLRVLHAAATIGIRGLIVHALTDSAKAFYERVGFEASPIDPMLLLITLADL
EHAL

Download         Length: 495 bp

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10198.49 Da        Isoelectric Point: 5.7881

>AT250345 WP_257819015.1 NZ_CP100242:58854-59135 [Burkholderia glumae]
MTSTTPRDTLNLRIRPDDRSLIDRAAVAAHKTRTDFVLDAARAAAEQTLLDQVVLSAEPQAYAAFLARLDAPAQPNEALR
QTMQTRAPWDPAA

Download         Length: 282 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References