Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpSB/PRK09812-ChpS
Location 10539..11134 Replicon plasmid p19s1p
Accession NZ_CP100235
Organism Burkholderia glumae strain BGR19S

Toxin (Protein)


Gene name chpB Uniprot ID C5AN78
Locus tag NIX15_RS29315 Protein ID WP_012734107.1
Coordinates 10784..11134 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name chpS Uniprot ID C5AN79
Locus tag NIX15_RS29310 Protein ID WP_012734108.1
Coordinates 10539..10790 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NIX15_RS29275 6158..6355 + 198 WP_127840952.1 hypothetical protein -
NIX15_RS29280 6748..7032 + 285 WP_017432347.1 hypothetical protein -
NIX15_RS29285 7046..7288 + 243 WP_124837682.1 hypothetical protein -
NIX15_RS29290 7285..7530 + 246 WP_127913916.1 hypothetical protein -
NIX15_RS29295 7587..7928 + 342 WP_012732710.1 hypothetical protein -
NIX15_RS29300 7931..9766 + 1836 WP_257811932.1 site-specific integrase -
NIX15_RS29305 9869..10276 + 408 WP_254613402.1 hypothetical protein -
NIX15_RS29310 10539..10790 + 252 WP_012734108.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
NIX15_RS29315 10784..11134 + 351 WP_012734107.1 type II toxin-antitoxin system ChpB family toxin Toxin
NIX15_RS29320 11193..11387 + 195 WP_124837685.1 hypothetical protein -
NIX15_RS29325 11537..11758 + 222 WP_017433768.1 hypothetical protein -
NIX15_RS29330 11981..12445 + 465 WP_012734106.1 Lrp/AsnC family transcriptional regulator -
NIX15_RS29335 12759..15134 + 2376 WP_232252305.1 TonB-dependent receptor -
NIX15_RS29340 15166..15912 + 747 WP_232252306.1 energy transducer TonB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - fliC 1..225605 225605


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(8-114)

Antitoxin

Antitoxin PemI-like

(1-83)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12389.37 Da        Isoelectric Point: 8.8909

>T250341 WP_012734107.1 NZ_CP100235:10784-11134 [Burkholderia glumae]
MVKRVKFERGDIVRVSLSPTVGREQQGDFRPALVLSPAAFNALGVALVAPITQGGEFARFAGFAVPLSGSGTETQGVALV
NMVRMLDLEGRGARKIERAPVEVVEDALARLQTIIE

Download         Length: 351 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 8940.31 Da        Isoelectric Point: 6.2420

>AT250341 WP_012734108.1 NZ_CP100235:10539-10790 [Burkholderia glumae]
MELKIQKWGNSAAVRLPSVLLEQINASVGGSLNADVRPDGVLLTPARRKYALDDLVAQCDTKAPVPADMAAWGEIKPVGR
EAW

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A246MF70

Antitoxin

Source ID Structure
AlphaFold DB A0A246MFN5

References