Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpSB/PRK09812-MazE
Location 122202..122797 Replicon plasmid pR52p
Accession NZ_CP100184
Organism Burkholderia glumae strain R5

Toxin (Protein)


Gene name chpB Uniprot ID -
Locus tag NIW68_RS30625 Protein ID WP_257820096.1
Coordinates 122202..122552 (-) Length 117 a.a.

Antitoxin (Protein)


Gene name chpS Uniprot ID -
Locus tag NIW68_RS30630 Protein ID WP_257820098.1
Coordinates 122546..122797 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NIW68_RS30580 118560..118790 - 231 WP_257820078.1 hypothetical protein -
NIW68_RS30585 118849..119058 - 210 WP_257820080.1 hypothetical protein -
NIW68_RS30590 119099..119473 - 375 WP_257820082.1 site-specific integrase -
NIW68_RS30595 119668..120054 - 387 WP_257820084.1 hypothetical protein -
NIW68_RS30600 120111..120494 - 384 WP_257820086.1 hypothetical protein -
NIW68_RS30605 120527..120919 - 393 WP_257820088.1 hypothetical protein -
NIW68_RS30610 121077..121385 - 309 WP_257820090.1 hypothetical protein -
NIW68_RS30615 121713..122000 - 288 WP_257820092.1 hypothetical protein -
NIW68_RS30620 122013..122189 - 177 WP_257820094.1 hypothetical protein -
NIW68_RS30625 122202..122552 - 351 WP_257820096.1 type II toxin-antitoxin system ChpB family toxin Toxin
NIW68_RS30630 122546..122797 - 252 WP_257820098.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
NIW68_RS30635 122945..125266 - 2322 WP_257820100.1 site-specific integrase -
NIW68_RS30640 125268..126089 - 822 WP_257820102.1 hypothetical protein -
NIW68_RS30645 126086..126415 - 330 WP_257820104.1 hypothetical protein -
NIW68_RS30650 126497..127294 - 798 WP_012732720.1 IS21-like element helper ATPase IstB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..172554 172554


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(7-116)

Antitoxin

Antitoxin PemI-like

(1-83)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12376.33 Da        Isoelectric Point: 8.6592

>T250304 WP_257820096.1 NZ_CP100184:c122552-122202 [Burkholderia glumae]
MVKRVKFERGDIVRVGLNPTMGKEQQGDFRPALVLSPAAFNALGVALVAPITQGGEFARYAGFAVPLSGSGTETQGVALV
NMVRTLDLEARGARKVERAPVEVVEDALARLQTILE

Download         Length: 351 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 8846.11 Da        Isoelectric Point: 4.6895

>AT250304 WP_257820098.1 NZ_CP100184:c122797-122546 [Burkholderia glumae]
MELKIQKWGNSAAVRLPAMLLEQIGASAGSSLTADVRPDGVLLTPARRKYSLDELVAQCDAKAPEPADLAAWGEVNAVGR
EAW

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References