Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) slvAT/RES(toxin)
Location 5410..6356 Replicon plasmid p49s2p
Accession NZ_CP100159
Organism Burkholderia glumae strain BGR49S

Toxin (Protein)


Gene name slvT Uniprot ID C5AN91
Locus tag NIW54_RS31070 Protein ID WP_012732709.1
Coordinates 5823..6356 (+) Length 178 a.a.

Antitoxin (Protein)


Gene name slvA Uniprot ID C5AN90
Locus tag NIW54_RS31065 Protein ID WP_012732708.1
Coordinates 5410..5826 (+) Length 139 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NIW54_RS31050 1342..2421 + 1080 WP_012732706.1 ParB N-terminal domain-containing protein -
NIW54_RS31055 2758..3663 + 906 WP_257765417.1 helix-turn-helix domain-containing protein -
NIW54_RS31060 5077..5262 + 186 WP_017432454.1 hypothetical protein -
NIW54_RS31065 5410..5826 + 417 WP_012732708.1 DUF2384 domain-containing protein Antitoxin
NIW54_RS31070 5823..6356 + 534 WP_012732709.1 RES family NAD+ phosphorylase Toxin
NIW54_RS31075 6526..6714 + 189 WP_017432455.1 hypothetical protein -
NIW54_RS31080 7465..7749 + 285 WP_017432347.1 hypothetical protein -
NIW54_RS31085 7763..8005 + 243 WP_124837682.1 hypothetical protein -
NIW54_RS31090 8002..8166 + 165 WP_257765418.1 hypothetical protein -
NIW54_RS31095 8305..8646 + 342 WP_012732710.1 hypothetical protein -
NIW54_RS31100 8649..10483 + 1835 Protein_12 site-specific integrase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..141000 141000


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(11-168)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 178 a.a.        Molecular weight: 19101.61 Da        Isoelectric Point: 4.7118

>T250286 WP_012732709.1 NZ_CP100159:5823-6356 [Burkholderia glumae]
MILTPLQDITAYRMHVPKWAVAPTSGAGAAKAGGRANRIGTPALYLALEAATAVAEYQQLSPLLPPGTLVSYRVTATPVV
DFTGGYRVDLWPPLWESFFCDWRHDWFNARIEPPSWVLGDEAIASGAKGILFRSTQAAGGTNLVLFVDQLGEGDRVDVHD
PAGALPRDQASWVDSPE

Download         Length: 534 bp

Antitoxin


Download         Length: 139 a.a.        Molecular weight: 14709.55 Da        Isoelectric Point: 6.4664

>AT250286 WP_012732708.1 NZ_CP100159:5410-5826 [Burkholderia glumae]
MSTLAAARAPAGGPALANFDAFLSALREPDTAAPVLSARRYVAALNIDLQTLADQAHVHRNTVARAPQSASVQQFLREAI
RVIRAATDLSGDVQRALFWYRNEPLAVFDYQTAETLVSAGRADDVVRYVASLEAGAAG

Download         Length: 417 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2J9GLU3

Antitoxin

Source ID Structure
AlphaFold DB A0A2J9GLX3

References