Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 1765..2302 Replicon plasmid p33s2p
Accession NZ_CP100143
Organism Burkholderia glumae strain BGR33S

Toxin (Protein)


Gene name parE Uniprot ID C5AN85
Locus tag NIV89_RS30415 Protein ID WP_012734112.1
Coordinates 2000..2302 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID C5AN86
Locus tag NIV89_RS30410 Protein ID WP_012734113.1
Coordinates 1765..2010 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NIV89_RS30405 1417..1611 + 195 WP_043308437.1 hypothetical protein -
NIV89_RS30410 1765..2010 + 246 WP_012734113.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
NIV89_RS30415 2000..2302 + 303 WP_012734112.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NIV89_RS30420 2462..2704 + 243 WP_043308436.1 hypothetical protein -
NIV89_RS30425 2912..3367 + 456 WP_012734111.1 hypothetical protein -
NIV89_RS30430 3371..3652 + 282 WP_043308454.1 type II toxin-antitoxin system RelE/ParE family toxin -
NIV89_RS30435 3830..4153 + 324 WP_043308435.1 hypothetical protein -
NIV89_RS30440 4541..4825 + 285 WP_017432347.1 hypothetical protein -
NIV89_RS30445 4839..5081 + 243 WP_124837682.1 hypothetical protein -
NIV89_RS30450 5078..5323 + 246 WP_127913916.1 hypothetical protein -
NIV89_RS30455 5380..5721 + 342 WP_012732710.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..185317 185317


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-92)

Antitoxin

Antitoxin ParD

(1-80)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11548.11 Da        Isoelectric Point: 6.7171

>T250275 WP_012734112.1 NZ_CP100143:2000-2302 [Burkholderia glumae]
MRGKARVVRLTPLAEADLEDIWAYIFEQWSLAQAEQYVGEIVAAFNRLARGEWVGAVRGEPYRRYLVGFHAVFYRETTDA
LDVACVRHQRMDVGSHLSQY

Download         Length: 303 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8645.69 Da        Isoelectric Point: 7.2029

>AT250275 WP_012734113.1 NZ_CP100143:1765-2010 [Burkholderia glumae]
MPRNTSISLGDHLTQFVDTQVASGRYGSASDVVRAGLRLLETQETELKALKEALRASEASGAPAAFDGQAFLDRMRAKHA
G

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB C5AN85

Antitoxin

Source ID Structure
AlphaFold DB C5AN86

References