Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | ParST/RES-TIGR02293 |
| Location | 2668092..2669092 | Replicon | chromosome |
| Accession | NZ_CP100128 | ||
| Organism | Chromobacterium sp. IIBBL 290-4 | ||
Toxin (Protein)
| Gene name | ParT | Uniprot ID | - |
| Locus tag | NKT35_RS12275 | Protein ID | WP_254293311.1 |
| Coordinates | 2668610..2669092 (+) | Length | 161 a.a. |
Antitoxin (Protein)
| Gene name | ParS | Uniprot ID | - |
| Locus tag | NKT35_RS12270 | Protein ID | WP_254293309.1 |
| Coordinates | 2668092..2668613 (+) | Length | 174 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NKT35_RS12245 (NKT35_12245) | 2663116..2663328 | + | 213 | WP_043578765.1 | 30S ribosomal protein S21 | - |
| NKT35_RS12250 (NKT35_12250) | 2663443..2663889 | + | 447 | WP_254293303.1 | GatB/YqeY domain-containing protein | - |
| NKT35_RS12255 (NKT35_12255) | 2663907..2665706 | + | 1800 | WP_254293305.1 | DNA primase | - |
| NKT35_RS12260 (NKT35_12260) | 2665784..2667709 | + | 1926 | WP_254293307.1 | RNA polymerase sigma factor RpoD | - |
| NKT35_RS12270 (NKT35_12270) | 2668092..2668613 | + | 522 | WP_254293309.1 | DUF2384 domain-containing protein | Antitoxin |
| NKT35_RS12275 (NKT35_12275) | 2668610..2669092 | + | 483 | WP_254293311.1 | RES family NAD+ phosphorylase | Toxin |
| NKT35_RS12280 (NKT35_12280) | 2669173..2670159 | - | 987 | WP_254293313.1 | zinc-binding dehydrogenase | - |
| NKT35_RS12285 (NKT35_12285) | 2670264..2671145 | + | 882 | WP_254293315.1 | LysR family transcriptional regulator | - |
| NKT35_RS12290 (NKT35_12290) | 2671232..2671996 | + | 765 | WP_254293317.1 | DUF1223 domain-containing protein | - |
| NKT35_RS12295 (NKT35_12295) | 2672070..2672414 | + | 345 | WP_254293319.1 | hypothetical protein | - |
| NKT35_RS12300 (NKT35_12300) | 2672499..2673419 | + | 921 | WP_254293321.1 | DUF3667 domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 161 a.a. Molecular weight: 17381.77 Da Isoelectric Point: 6.4689
>T250260 WP_254293311.1 NZ_CP100128:2668610-2669092 [Chromobacterium sp. IIBBL 290-4]
VTRLAWRIATDTPDYSAEDMSGEGAKRTGGRWNRRGGAMLYSAESRALACLETLAHLGAGGLPLNRYLVRLEIPDAVWAR
AERVSPDDSALVGWDALPAGRVSLDYGDGWLRESRSALLLVPSIIVAEESNILINPAHPDAAAICAVKVRKWQYDARLAV
VTRLAWRIATDTPDYSAEDMSGEGAKRTGGRWNRRGGAMLYSAESRALACLETLAHLGAGGLPLNRYLVRLEIPDAVWAR
AERVSPDDSALVGWDALPAGRVSLDYGDGWLRESRSALLLVPSIIVAEESNILINPAHPDAAAICAVKVRKWQYDARLAV
Download Length: 483 bp
Antitoxin
Download Length: 174 a.a. Molecular weight: 19316.23 Da Isoelectric Point: 5.7521
>AT250260 WP_254293309.1 NZ_CP100128:2668092-2668613 [Chromobacterium sp. IIBBL 290-4]
MAMRQAHRVSDPPVRESSHPETGSYLLEKPSITHFLRLYRLSPMERIDLILRGVPAAEAKEVAKRMDVAQDAMFKVLRLP
ISTVNKRAARNQELTIEESERLVGMASLIGQVESMMAESGEAEDFDAAKWLGQWMETPNPALGQRRPAEFLCTAEGFRLV
SDVLAAMQSGAYL
MAMRQAHRVSDPPVRESSHPETGSYLLEKPSITHFLRLYRLSPMERIDLILRGVPAAEAKEVAKRMDVAQDAMFKVLRLP
ISTVNKRAARNQELTIEESERLVGMASLIGQVESMMAESGEAEDFDAAKWLGQWMETPNPALGQRRPAEFLCTAEGFRLV
SDVLAAMQSGAYL
Download Length: 522 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|