Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2024639..2024784 | Replicon | chromosome |
| Accession | NZ_CP100110 | ||
| Organism | Klebsiella pneumoniae strain HSKP104 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2024675..2024777 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2024639..2024784 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NIL12_RS09795 | 2019769..2021829 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| NIL12_RS09800 | 2021833..2022492 | - | 660 | WP_020324964.1 | exodeoxyribonuclease X | - |
| NIL12_RS09805 | 2022571..2022801 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| NIL12_RS09810 | 2022914..2023288 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| NIL12_RS09815 | 2023292..2024161 | + | 870 | WP_004151447.1 | copper homeostasis membrane protein CopD | - |
| NIL12_RS09820 | 2024178..2024516 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 2024639..2024784 | - | 146 | - | - | Antitoxin |
| - | 2024675..2024777 | + | 103 | - | - | Toxin |
| NIL12_RS09825 | 2025153..2025296 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| NIL12_RS09830 | 2025401..2026369 | - | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| NIL12_RS09835 | 2026526..2027179 | + | 654 | WP_004180432.1 | protein-serine/threonine phosphatase | - |
| NIL12_RS09840 | 2027176..2027367 | - | 192 | WP_002911395.1 | YebW family protein | - |
| NIL12_RS09845 | 2027465..2027704 | - | 240 | WP_002911393.1 | YebV family protein | - |
| NIL12_RS09850 | 2027820..2029253 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T250190 NZ_CP100110:2024675-2024777 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT250190 NZ_CP100110:c2024784-2024639 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
