Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4904199..4904344 Replicon chromosome
Accession NZ_CP100102
Organism Klebsiella pneumoniae strain HSKP33

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4904235..4904337 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4904199..4904344 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NIL14_RS23520 4899329..4901389 + 2061 WP_004151449.1 oligopeptidase B -
NIL14_RS23525 4901393..4902052 - 660 WP_020324964.1 exodeoxyribonuclease X -
NIL14_RS23530 4902131..4902361 - 231 WP_002911406.1 DNA polymerase III subunit theta -
NIL14_RS23535 4902474..4902848 + 375 WP_004151448.1 CopC domain-containing protein YobA -
NIL14_RS23540 4902852..4903721 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
NIL14_RS23545 4903738..4904076 + 339 WP_002911404.1 YebY family protein -
- 4904199..4904344 - 146 - - Antitoxin
- 4904235..4904337 + 103 - - Toxin
NIL14_RS23550 4904713..4904856 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
NIL14_RS23555 4904961..4905929 - 969 WP_004151446.1 VirK/YbjX family protein -
NIL14_RS23560 4906086..4906739 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
NIL14_RS23565 4906736..4906927 - 192 WP_002911395.1 YebW family protein -
NIL14_RS23570 4907025..4907264 - 240 WP_002911393.1 YebV family protein -
NIL14_RS23575 4907380..4908813 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T250159 NZ_CP100102:4904235-4904337 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT250159 NZ_CP100102:c4904344-4904199 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References