Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2025936..2026081 | Replicon | chromosome |
| Accession | NZ_CP100084 | ||
| Organism | Klebsiella pneumoniae strain HSKP86 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2025972..2026074 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2025936..2026081 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NIL18_RS09795 | 2021066..2023126 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| NIL18_RS09800 | 2023130..2023789 | - | 660 | WP_020324964.1 | exodeoxyribonuclease X | - |
| NIL18_RS09805 | 2023868..2024098 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| NIL18_RS09810 | 2024211..2024585 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| NIL18_RS09815 | 2024589..2025458 | + | 870 | WP_004151447.1 | copper homeostasis membrane protein CopD | - |
| NIL18_RS09820 | 2025475..2025813 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 2025936..2026081 | - | 146 | - | - | Antitoxin |
| - | 2025972..2026074 | + | 103 | - | - | Toxin |
| NIL18_RS09825 | 2026450..2026593 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| NIL18_RS09830 | 2026698..2027666 | - | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| NIL18_RS09835 | 2027823..2028476 | + | 654 | WP_004180432.1 | protein-serine/threonine phosphatase | - |
| NIL18_RS09840 | 2028473..2028664 | - | 192 | WP_002911395.1 | YebW family protein | - |
| NIL18_RS09845 | 2028762..2029001 | - | 240 | WP_002911393.1 | YebV family protein | - |
| NIL18_RS09850 | 2029117..2030550 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T250075 NZ_CP100084:2025972-2026074 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT250075 NZ_CP100084:c2026081-2025936 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
