Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1922726..1922871 Replicon chromosome
Accession NZ_CP100076
Organism Klebsiella pneumoniae strain RJKP36

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1922762..1922864 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1922726..1922871 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NIL00_RS09185 1917856..1919916 + 2061 WP_004151449.1 oligopeptidase B -
NIL00_RS09190 1919920..1920579 - 660 WP_020324964.1 exodeoxyribonuclease X -
NIL00_RS09195 1920658..1920888 - 231 WP_002911406.1 DNA polymerase III subunit theta -
NIL00_RS09200 1921001..1921375 + 375 WP_004151448.1 CopC domain-containing protein YobA -
NIL00_RS09205 1921379..1922248 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
NIL00_RS09210 1922265..1922603 + 339 WP_002911404.1 YebY family protein -
- 1922726..1922871 - 146 - - Antitoxin
- 1922762..1922864 + 103 - - Toxin
NIL00_RS09215 1923240..1923383 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
NIL00_RS09220 1923488..1924456 - 969 WP_004151446.1 VirK/YbjX family protein -
NIL00_RS09225 1924613..1925266 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
NIL00_RS09230 1925263..1925454 - 192 WP_002911395.1 YebW family protein -
NIL00_RS09235 1925552..1925791 - 240 WP_002911393.1 YebV family protein -
NIL00_RS09240 1925907..1927340 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T250058 NZ_CP100076:1922762-1922864 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT250058 NZ_CP100076:c1922871-1922726 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References