Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2025553..2025698 Replicon chromosome
Accession NZ_CP100072
Organism Klebsiella pneumoniae strain RJKP41

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2025589..2025691 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2025553..2025698 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NIL01_RS09795 2020683..2022743 + 2061 WP_004151449.1 oligopeptidase B -
NIL01_RS09800 2022747..2023406 - 660 WP_020324964.1 exodeoxyribonuclease X -
NIL01_RS09805 2023485..2023715 - 231 WP_002911406.1 DNA polymerase III subunit theta -
NIL01_RS09810 2023828..2024202 + 375 WP_004151448.1 CopC domain-containing protein YobA -
NIL01_RS09815 2024206..2025075 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
NIL01_RS09820 2025092..2025430 + 339 WP_002911404.1 YebY family protein -
- 2025553..2025698 - 146 - - Antitoxin
- 2025589..2025691 + 103 - - Toxin
NIL01_RS09825 2026067..2026210 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
NIL01_RS09830 2026315..2027283 - 969 WP_004151446.1 VirK/YbjX family protein -
NIL01_RS09835 2027440..2028093 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
NIL01_RS09840 2028090..2028281 - 192 WP_002911395.1 YebW family protein -
NIL01_RS09845 2028379..2028618 - 240 WP_002911393.1 YebV family protein -
NIL01_RS09850 2028734..2030167 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T250034 NZ_CP100072:2025589-2025691 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT250034 NZ_CP100072:c2025698-2025553 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References