Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 1923335..1923988 Replicon chromosome
Accession NZ_CP099989
Organism Acinetobacter baumannii strain KBN10P04593

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag NIH92_RS09325 Protein ID WP_000607077.1
Coordinates 1923599..1923988 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag NIH92_RS09320 Protein ID WP_001288210.1
Coordinates 1923335..1923592 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NIH92_RS09300 (NIH92_09300) 1918851..1919858 + 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -
NIH92_RS09305 (NIH92_09305) 1919877..1920254 + 378 WP_001216380.1 50S ribosomal protein L17 -
NIH92_RS09310 (NIH92_09310) 1920436..1921926 + 1491 WP_000415125.1 NAD(P)/FAD-dependent oxidoreductase -
NIH92_RS09315 (NIH92_09315) 1921975..1923147 - 1173 WP_001190542.1 acyl-CoA dehydrogenase family protein -
NIH92_RS09320 (NIH92_09320) 1923335..1923592 + 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
NIH92_RS09325 (NIH92_09325) 1923599..1923988 + 390 WP_000607077.1 membrane protein Toxin
NIH92_RS09330 (NIH92_09330) 1924758..1925843 + 1086 WP_000049106.1 hypothetical protein -
NIH92_RS09335 (NIH92_09335) 1925921..1926487 + 567 WP_000651538.1 rhombosortase -
NIH92_RS09340 (NIH92_09340) 1926675..1928870 + 2196 WP_001158906.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15552.88 Da        Isoelectric Point: 10.4313

>T250025 WP_000607077.1 NZ_CP099989:1923599-1923988 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT250025 WP_001288210.1 NZ_CP099989:1923335-1923592 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References