Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yafQ-relB/YafQ-RelB
Location 14955..15484 Replicon plasmid unnamed1
Accession NZ_CP099976
Organism Halomonas sp. Y3

Toxin (Protein)


Gene name yafQ Uniprot ID -
Locus tag NHL60_RS19490 Protein ID WP_253452412.1
Coordinates 14955..15227 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NHL60_RS19495 Protein ID WP_253452415.1
Coordinates 15227..15484 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NHL60_RS19445 10747..11436 + 690 WP_253452451.1 hypothetical protein -
NHL60_RS19450 11440..11700 + 261 WP_253452456.1 hypothetical protein -
NHL60_RS19455 11877..12194 - 318 WP_253452459.1 hypothetical protein -
NHL60_RS19460 12196..12486 - 291 WP_253452395.1 hypothetical protein -
NHL60_RS19465 12625..12876 + 252 WP_253452398.1 helix-turn-helix transcriptional regulator -
NHL60_RS19470 13259..13384 - 126 WP_253452401.1 carbohydrate porin -
NHL60_RS19475 13402..13644 - 243 WP_253452403.1 hypothetical protein -
NHL60_RS19480 14024..14314 - 291 WP_253452406.1 hypothetical protein -
NHL60_RS19485 14502..14837 + 336 WP_253452409.1 type II toxin-antitoxin system HicB family antitoxin -
NHL60_RS19490 14955..15227 - 273 WP_253452412.1 type II toxin-antitoxin system YafQ family toxin Toxin
NHL60_RS19495 15227..15484 - 258 WP_253452415.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
NHL60_RS19500 15661..19155 + 3495 WP_253452418.1 hypothetical protein -
NHL60_RS19505 20106..20357 + 252 WP_253452421.1 DUF2384 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..24166 24166


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-88)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-83)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10637.19 Da        Isoelectric Point: 9.5902

>T250023 WP_253452412.1 NZ_CP099976:c15227-14955 [Halomonas sp. Y3]
MLTPVRTSQFKRDVKRVQKRGKDMTKLRTLLGLLIEQAPLPEAYQDHPLRGNWNGYRDAHIEPDWLLLYRIVDDELHLSR
TGSHADLFRE

Download         Length: 273 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9237.59 Da        Isoelectric Point: 4.7872

>AT250023 WP_253452415.1 NZ_CP099976:c15484-15227 [Halomonas sp. Y3]
MSADTVVRARIDSETKERATAALEAMGLSVSDAIRLLMLRIADEKRLPFAVQVPNATTTKAMAELDAGKGKRFDNADELF
QDLGI

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References