Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/COG3657-dnstrm_HI1420
Location 2326816..2327430 Replicon chromosome
Accession NZ_CP099975
Organism Halomonas sp. Y3

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag NHL60_RS11125 Protein ID WP_253443270.1
Coordinates 2326816..2327112 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NHL60_RS11130 Protein ID WP_253443271.1
Coordinates 2327116..2327430 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NHL60_RS11105 2322876..2323544 + 669 WP_253443269.1 IS4 family transposase -
NHL60_RS11110 2323572..2324345 - 774 WP_133483961.1 IS21-like element helper ATPase IstB -
NHL60_RS11115 2324338..2325828 - 1491 WP_253452147.1 IS21 family transposase -
NHL60_RS11120 2325964..2326515 + 552 WP_253452150.1 transposase -
NHL60_RS11125 2326816..2327112 + 297 WP_253443270.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NHL60_RS11130 2327116..2327430 + 315 WP_253443271.1 putative addiction module antidote protein Antitoxin
NHL60_RS11135 2328373..2329549 + 1177 Protein_2164 group II intron reverse transcriptase/maturase -
NHL60_RS11140 2329618..2330994 - 1377 WP_253443272.1 IS4 family transposase -
NHL60_RS11145 2331139..2331606 - 468 WP_253443273.1 transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2319954..2332505 12551


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-96)

Antitoxin

Cro/C1-type helix-turn-helix domain

(50-93)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11026.86 Da        Isoelectric Point: 10.5786

>T250020 WP_253443270.1 NZ_CP099975:2326816-2327112 [Halomonas sp. Y3]
MIELIKTDVFDRWLRSLRDTRARAKITVRLRRLSLGNPGDVKPVGEGISELRIPHGPGYRVYYLTRGPIVVVLLCGGDKG
SQPSDIEQAKAIAKQWKE

Download         Length: 297 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11170.62 Da        Isoelectric Point: 4.2837

>AT250020 WP_253443271.1 NZ_CP099975:2327116-2327430 [Halomonas sp. Y3]
MATQQQVTFSHYDTAEYLQTEEEIAAYLEAVMEENDPSLLAAALGDVARARNMSQLAKEVGMSREGLYKALSGEGNPAFS
TINKVANALGLQLTIKPMSPPPAP

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References