Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 3830092..3830668 Replicon chromosome
Accession NZ_CP099965
Organism Halomonas sp. DN3

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NKF27_RS16470 Protein ID WP_253553357.1
Coordinates 3830375..3830668 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NKF27_RS16465 Protein ID WP_253553354.1
Coordinates 3830092..3830388 (+) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NKF27_RS16445 (NKF27_16445) 3825210..3827285 + 2076 WP_253553334.1 GGDEF domain-containing protein -
NKF27_RS16450 (NKF27_16450) 3827372..3827824 - 453 WP_253553337.1 tRNA adenosine(34) deaminase TadA -
NKF27_RS16455 (NKF27_16455) 3827947..3828762 + 816 WP_108132364.1 acyl-CoA thioesterase II -
NKF27_RS16460 (NKF27_16460) 3828883..3829203 - 321 WP_253553351.1 DNA-binding protein -
NKF27_RS16465 (NKF27_16465) 3830092..3830388 + 297 WP_253553354.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
NKF27_RS16470 (NKF27_16470) 3830375..3830668 + 294 WP_253553357.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NKF27_RS16475 (NKF27_16475) 3830672..3831004 + 333 WP_253553360.1 Rha family transcriptional regulator -
NKF27_RS16480 (NKF27_16480) 3831027..3831380 - 354 WP_253553363.1 DUF488 family protein -
NKF27_RS16485 (NKF27_16485) 3831579..3831788 - 210 WP_108132360.1 hypothetical protein -
NKF27_RS16490 (NKF27_16490) 3831878..3832801 - 924 WP_253553366.1 ectoine hydroxylase -
NKF27_RS16495 (NKF27_16495) 3832980..3833726 + 747 WP_253553368.1 Crp/Fnr family transcriptional regulator -
NKF27_RS16500 (NKF27_16500) 3834005..3834706 + 702 WP_108132359.1 GntR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-53)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11212.09 Da        Isoelectric Point: 8.4716

>T249993 WP_253553357.1 NZ_CP099965:3830375-3830668 [Halomonas sp. DN3]
MVKIEWSILALKDASGIVEYISEDTPDAALKLFHHIKNKVDRLPDHPKLYKPGREPRTREMVVTDNYIVVYRESEALITI
LRVLHAAQKMALESKKE

Download         Length: 294 bp

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 10713.14 Da        Isoelectric Point: 5.9706

>AT249993 WP_253553354.1 NZ_CP099965:3830092-3830388 [Halomonas sp. DN3]
MARTTMLHVRVDEDLKAEATETLAKVGLTVSEAVRILLTRVSAEGGLPAGLTSDPQAHDAWFRMKVQEALADTRQGIPHD
HAMSHIQAIIESKRNGED

Download         Length: 297 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References