Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 305005..305805 Replicon chromosome
Accession NZ_CP099914
Organism Escherichia albertii strain 104_2_TS_A

Toxin (Protein)


Gene name ataT Uniprot ID B1EHN9
Locus tag NIY84_RS01415 Protein ID WP_000342453.1
Coordinates 305278..305805 (+) Length 176 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID B1EHP0
Locus tag NIY84_RS01410 Protein ID WP_001277106.1
Coordinates 305005..305271 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NIY84_RS01385 (300726) 300726..301580 - 855 WP_000370584.1 PTS system mannose/fructose/sorbose family transporter subunit IID -
NIY84_RS01390 (301573) 301573..302319 - 747 WP_000151888.1 PTS sugar transporter subunit IIC -
NIY84_RS01395 (302336) 302336..302821 - 486 WP_000029259.1 PTS sugar transporter subunit IIB -
NIY84_RS01400 (302828) 302828..303229 - 402 WP_001071334.1 PTS sugar transporter subunit IIA -
NIY84_RS01405 (303752) 303752..304855 + 1104 WP_010319184.1 branched chain amino acid ABC transporter substrate-binding protein LivJ -
NIY84_RS01410 (305005) 305005..305271 + 267 WP_001277106.1 type II toxin-antitoxin system antitoxin AtaR Antitoxin
NIY84_RS01415 (305278) 305278..305805 + 528 WP_000342453.1 type II toxin-antitoxin system toxin acetyltransferase AtaT Toxin
NIY84_RS01420 (305802) 305802..306185 - 384 WP_000778774.1 aspartate 1-decarboxylase autocleavage activator PanM -
NIY84_RS01425 (306609) 306609..307718 + 1110 WP_256879195.1 high-affinity branched-chain amino acid ABC transporter substrate-binding protein LivK -
NIY84_RS01430 (307766) 307766..308692 + 927 WP_001295111.1 high-affinity branched-chain amino acid ABC transporter permease LivH -
NIY84_RS01435 (308689) 308689..309966 + 1278 WP_256879194.1 branched chain amino acid ABC transporter permease LivM -
NIY84_RS01440 (309963) 309963..310730 + 768 WP_000082101.1 high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivG -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(88-150)

Antitoxin

Vibrio phage ICP1, Orf50

(8-86)


Sequences

Toxin        


Download         Length: 176 a.a.        Molecular weight: 19676.58 Da        Isoelectric Point: 6.9585

>T249970 WP_000342453.1 NZ_CP099914:305278-305805 [Escherichia albertii]
MDDLTIEILTDDADYDLQRFDCGEEALNLFLTTHLVRQHRNKILRAYILCRNTPERQVLGYYTLSGSCFERAALPSKSKQ
KKIPYKNIPSVTLGRLAIDRSLQGQGWGATLVAHAMKVVWSASLAVGIHGLFVEALNEKAHTFYQSLGFIPLVGENENAL
FFPTKSIELLFTQSD

Download         Length: 528 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9942.37 Da        Isoelectric Point: 10.0863

>AT249970 WP_001277106.1 NZ_CP099914:305005-305271 [Escherichia albertii]
MSAVKKQRIDLRLTDDDKSMIEEAAAISNQSVSQFMLNSASQRAAEVIEQHRRMILNEESWTRVMDALSNPPSPGEKLKR
AAKRLQGM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7Z8E004

References