Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2015065..2015296 Replicon chromosome
Accession NZ_CP099912
Organism Escherichia albertii strain 105_1_LWG_A

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2015193..2015295 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2015065..2015296 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NIY85_RS09750 2011615..2012277 - 663 WP_025238865.1 exodeoxyribonuclease X -
NIY85_RS09755 2012301..2012957 - 657 WP_025238866.1 carbon-nitrogen hydrolase family protein YobB -
NIY85_RS09760 2013059..2013289 - 231 WP_000916758.1 DNA polymerase III subunit theta -
NIY85_RS09765 2013428..2013805 + 378 WP_256876740.1 CopC domain-containing protein YobA -
NIY85_RS09770 2013809..2014681 + 873 WP_025238867.1 copper homeostasis membrane protein CopD -
NIY85_RS09775 2014694..2015035 + 342 WP_000976487.1 DUF2511 domain-containing protein -
- 2015065..2015296 - 232 - - Antitoxin
- 2015193..2015295 + 103 - - Toxin
NIY85_RS09780 2015427..2016503 - 1077 WP_256876741.1 phage integrase Arm DNA-binding domain-containing protein -
NIY85_RS09785 2016469..2016750 - 282 WP_001311878.1 excisionase -
NIY85_RS09790 2016857..2017045 - 189 WP_001356607.1 DUF1187 family protein -
- 2016861..2017039 + 179 NuclAT_0 - -
- 2016861..2017039 + 179 NuclAT_0 - -
- 2016861..2017039 + 179 NuclAT_0 - -
- 2016861..2017039 + 179 NuclAT_0 - -
NIY85_RS09795 2017038..2017232 - 195 WP_042853000.1 type I toxin-antitoxin system endodeoxyribonuclease toxin RalR -
NIY85_RS09800 2017289..2018098 - 810 WP_000166317.1 recombination protein RecT -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2015427..2028265 12838
- inside Prophage - - 1946108..2079226 133118


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T249948 NZ_CP099912:2015193-2015295 [Escherichia albertii]
GCAAGGCAACTGAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAAAACA
GGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 232 bp

>AT249948 NZ_CP099912:c2015296-2015065 [Escherichia albertii]
TAAAAAAAGACCGAATACGATTCCTGTTTTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTCAGTTGCCTTGCTCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTACAAAATGGTCAGT
AAAAAGCGCGTCGGCCATCGTCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGTGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References